State of the art CRISPR-based strategies for cancer diagnostics and treatment
E Di Carlo, C Sorrentino - Biomarker Research, 2024 - Springer
Abstract Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology
is a groundbreaking and dynamic molecular tool for DNA and RNA “surgery”. CRISPR/Cas9 …
is a groundbreaking and dynamic molecular tool for DNA and RNA “surgery”. CRISPR/Cas9 …
Targeting Noncoding cis-Regulatory Elements for Cancer Therapy in the Context of the 3D Genome
K Li, GH Wei, Y Yin, J Feng - Cancer Discovery, 2024 - aacrjournals.org
Significant efforts have been made to identify and validate oncoproteins and ncRNAs as
therapeutic targets for cancer therapy; however, emerging observations suggest that …
therapeutic targets for cancer therapy; however, emerging observations suggest that …
[HTML][HTML] A Novel AKT1, ERBB2, ESR1, KRAS, PIK3CA, and TP53 NGS Assay: A Non-Invasive Tool to Monitor Resistance Mechanisms to Hormonal Therapy and …
Background: Patients with hormone receptor-positive (HR+)/HER2-metastatic breast cancer
(mBC) generally receive hormonal therapy (HT) combined with CDK4/6 inhibitors (CDK4/6i) …
(mBC) generally receive hormonal therapy (HT) combined with CDK4/6 inhibitors (CDK4/6i) …