Nucleic acid-based wearable and implantable electrochemical sensors
The rapid advancements in nucleic acid-based electrochemical sensors for implantable and
wearable applications have marked a significant leap forward in the domain of personal …
wearable applications have marked a significant leap forward in the domain of personal …
Computational tools for aptamer identification and optimization
D Sun, M Sun, J Zhang, X Lin, Y Zhang, F Lin… - TrAC Trends in …, 2022 - Elsevier
Aptamers are single-stranded DNA or RNA oligonucleotides that can selectively bind to a
specific target. They are generally obtained by SELEX, but the procedure is challenging and …
specific target. They are generally obtained by SELEX, but the procedure is challenging and …
Design and prediction of aptamers assisted by in silico methods
SJ Lee, J Cho, BH Lee, D Hwang, JW Park - Biomedicines, 2023 - mdpi.com
An aptamer is a single-stranded DNA or RNA that binds to a specific target with high binding
affinity. Aptamers are developed through the process of systematic evolution of ligands by …
affinity. Aptamers are developed through the process of systematic evolution of ligands by …
Recent trends in RNA informatics: a review of machine learning and deep learning for RNA secondary structure prediction and RNA drug discovery
Computational analysis of RNA sequences constitutes a crucial step in the field of RNA
biology. As in other domains of the life sciences, the incorporation of artificial intelligence …
biology. As in other domains of the life sciences, the incorporation of artificial intelligence …
Application of machine learning on understanding biomolecule interactions in cellular machinery
Abstract Machine learning (ML) applications have become ubiquitous in all fields of
research including protein science and engineering. Apart from protein structure and …
research including protein science and engineering. Apart from protein structure and …
A review of machine learning approaches for drug synergy prediction in cancer
A Torkamannia, Y Omidi… - Briefings in Bioinformatics, 2022 - academic.oup.com
Combinational pharmacotherapy with the synergistic/additive effect is a powerful treatment
strategy for complex diseases such as malignancies. Identifying synergistic combinations …
strategy for complex diseases such as malignancies. Identifying synergistic combinations …
Predicting RNA structures and functions by artificial intelligence
RNA functions by interacting with its intended targets structurally. However, due to the
dynamic nature of RNA molecules, RNA structures are difficult to determine experimentally …
dynamic nature of RNA molecules, RNA structures are difficult to determine experimentally …
Electrochemical aptasensors for antibiotics detection: Recent achievements and applications for monitoring food safety
G Evtugyn, A Porfireva, G Tsekenis, V Oravczova… - Sensors, 2022 - mdpi.com
Antibiotics are often used in human and veterinary medicine for the treatment of bacterial
diseases. However, extensive use of antibiotics in agriculture can result in the contamination …
diseases. However, extensive use of antibiotics in agriculture can result in the contamination …
Smart approach for the design of highly selective aptamer-based biosensors
Aptamers are chemically synthesized single-stranded DNA or RNA oligonucleotides widely
used nowadays in sensors and nanoscale devices as highly sensitive biorecognition …
used nowadays in sensors and nanoscale devices as highly sensitive biorecognition …
[HTML][HTML] Current developments of SELEX technologies and prospects in the aptamer selection with clinical applications
DJ Chinchilla-Cárdenas, JS Cruz-Méndez… - Journal of Genetic …, 2024 - Elsevier
Aptamers are single-stranded oligonucleotide sequences capable of binding to specific
ligands with high affinity. In this manner, they are like antibodies but have advantages such …
ligands with high affinity. In this manner, they are like antibodies but have advantages such …