Wnts are secreted, lipid-modified proteins that bind to different receptors on the cell surface
to activate canonical or non-canonical Wnt signaling pathways, which control various …

Wnt signaling has multiple functions beyond the transcriptional effects of β-catenin
stabilization. We review recent investigations that uncover new cell physiological effects …

Wnt/β‐catenin signaling is an ancient pathway that regulates key aspects of embryonic
development, cell differentiation, proliferation, and adult stem cell homeostasis. Work from …

Wnt signaling plays crucial roles in development and tissue homeostasis, and its
dysregulation leads to various diseases, notably cancer. Wnt/β-catenin signaling is initiated …

Developmental biology has contributed greatly to evolutionary biology in the past century.
With the discovery that vertebrates share Hox genes with Drosophila in 1984, it became …

Wnt signalling plays an eminent role in development, stem cell growth, and tissue
homeostasis. Much of what we know about Wnt signalling, we owe to research in …

The WNT/β-catenin signalling pathway is a rich and complex network of cellular proteins that
orchestrates diverse short-range cell-to-cell communication in metazoans and is essential …

The nutrient-sensing metabolite S-adenosylmethionine (SAM) controls one-carbon
metabolism by donating methyl groups to biochemical building blocks, DNA, RNA, and …

To analyze the anti-tumor mechanism of Baicalin in human colon cancer. The MTT assay
and colony formation assay demonstrated that Baicalin treatment inhibits the proliferation of …

A hallmark of Spemann organizer function is its expression of Wnt antagonists that regulate
axial embryonic patterning. Here we identify the tumor suppressor Protein tyrosine …