Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …

Tissue engineering (TE) aims to regenerate critical size defects, which cannot heal naturally,
by using highly porous matrices called TE scaffolds made of biocompatible and …

Nerve injuries and neurodegenerative disorders remain serious challenges, owing to the
poor treatment outcomes of in situ neural stem cell regeneration. The most promising …

High internal phase emulsions (HIPEs), with densely packed droplets of internal phase and
monomers dispersed in the continuous phase, are now an established medium for porous …

Abstract Three-dimensional (3D) cell cultures offer an unparalleled platform to recreate
spatial arrangements of cells in vitro. 3D cell culture systems have gained increasing interest …

Bi-dimensional culture systems have represented the most used method to study cell
biology outside the body for over a century. Although they convey useful information, such …

In vivo, cells reside in a 3D porous and dynamic microenvironment. It provides biochemical
and biophysical cues that regulate cell behavior in physiological and pathological …

Scaffolds for bone defect treatment should ideally support vascularization and promote bone
formation, to facilitate the translation into biomedical device applications. This study presents …

Repairing the human brain remains a challenge, despite the advances in the knowledge of
inflammatory response to injuries and the discovery of adult neurogenesis. After brain injury …

The use of human neural stem cells (hNSCs) for clinical cell therapies is limited by the lack
of effective culture substrates to produce hNSCs. Animal-sourced substrates could result in …