Cancer evolution: Darwin and beyond
Clinical and laboratory studies over recent decades have established branched evolution as
a feature of cancer. However, while grounded in somatic selection, several lines of evidence …
a feature of cancer. However, while grounded in somatic selection, several lines of evidence …
Using circulating tumor DNA in colorectal cancer: current and evolving practices
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
Preoperative chemotherapy for operable colon cancer: mature results of an international randomized controlled trial
PURPOSE Neoadjuvant chemotherapy (NAC) has potential advantages over standard
postoperative chemotherapy for locally advanced colon cancer but requires formal …
postoperative chemotherapy for locally advanced colon cancer but requires formal …
Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a …
F Quénet, D Elias, L Roca, D Goéré, L Ghouti… - The Lancet …, 2021 - thelancet.com
Background The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to
cytoreductive surgery has been associated with encouraging survival results in some …
cytoreductive surgery has been associated with encouraging survival results in some …
The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of colon cancer
METHODS This guideline is based on the previous colon cancer parameter published in
2017. 10 Compared with 2017, this guideline has 11 new, 10 updated, and 2 excluded …
2017. 10 Compared with 2017, this guideline has 11 new, 10 updated, and 2 excluded …
Adjuvant therapy for stage II colon cancer: ASCO guideline update
NN Baxter, EB Kennedy, E Bergsland… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To develop recommendations for adjuvant therapy for patients with resected
stage II colon cancer. METHODS ASCO convened an Expert Panel to conduct a systematic …
stage II colon cancer. METHODS ASCO convened an Expert Panel to conduct a systematic …
[HTML][HTML] Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Colorectal cancer (CRC) is the third most common tumour in men and the second in women,
accounting for 10% of all tumour types worldwide. Incidence is 25% higher in males and …
accounting for 10% of all tumour types worldwide. Incidence is 25% higher in males and …
[HTML][HTML] Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer
Y Hashiguchi, K Muro, Y Saito, Y Ito, Y Ajioka… - International journal of …, 2020 - Springer
The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …
Adipocyte‐derived exosomal MTTP suppresses ferroptosis and promotes chemoresistance in colorectal cancer
Q Zhang, T Deng, H Zhang, D Zuo, Q Zhu… - Advanced …, 2022 - Wiley Online Library
Obesity is closely related to a poor prognosis in patients with advanced colorectal cancer
(CRC), but the mechanisms remain unclear. Ferroptosis is a form of nonapoptotic cell death …
(CRC), but the mechanisms remain unclear. Ferroptosis is a form of nonapoptotic cell death …
Circulating tumor DNA in stage III colorectal cancer, beyond minimal residual disease detection, toward assessment of adjuvant therapy efficacy and clinical behavior …
TV Henriksen, N Tarazona, A Frydendahl… - Clinical Cancer …, 2022 - AACR
Purpose: Sensitive methods for risk stratification, monitoring therapeutic efficacy, and early
relapse detection may have a major impact on treatment decisions and patient management …
relapse detection may have a major impact on treatment decisions and patient management …