Allogeneic vs. autologous mesenchymal stem/stromal cells in their medication practice

C Li, H Zhao, L Cheng, B Wang - Cell & Bioscience, 2021 - Springer
Mesenchymal stem/stromal cell (MSC)-based therapeutics is already available for treatment
of a range of diseases or medical conditions. Autologous or allogeneic MSCs obtained from …

Mesenchymal stromal cell-based therapy for cartilage regeneration in knee osteoarthritis

XN Xiang, SY Zhu, HC He, X Yu, Y Xu… - Stem cell research & …, 2022 - Springer
Osteoarthritis, as a degenerative disease, is a common problem and results in high
socioeconomic costs and rates of disability. The most commonly affected joint is the knee …

Mesenchymal stem cells derived from perinatal tissues for treatment of critically ill COVID-19-induced ARDS patients: a case series

SMR Hashemian, R Aliannejad, M Zarrabi… - Stem cell research & …, 2021 - Springer
Background Acute respiratory distress syndrome (ARDS) is a fatal complication of
coronavirus disease 2019 (COVID-19). There are a few reports of allogeneic human …

[HTML][HTML] Harnessing knee joint resident mesenchymal stem cells in cartilage tissue engineering

X Xu, L Xu, J Xia, C Wen, Y Liang, Y Zhang - Acta Biomaterialia, 2023 - Elsevier
Osteoarthritis (OA) is a widespread clinical disease characterized by cartilage degeneration
in middle-aged and elderly people. Currently, there is no effective treatment for OA apart …

Articular cartilage regeneration in osteoarthritis

L Roseti, G Desando, C Cavallo, M Petretta, B Grigolo - Cells, 2019 - mdpi.com
There has been considerable advancement over the last few years in the treatment of
osteoarthritis, common chronic disease and a major cause of disability in older adults. In this …

Research progress in the use of mesenchymal stem cells and their derived exosomes in the treatment of osteoarthritis

H Yu, Y Huang, L Yang - Ageing research reviews, 2022 - Elsevier
Osteoarthritis (OA), as a common orthopedic disease with cartilage injury as its main
pathological feature, has a complex pathogenesis and existing medical technology remains …

[HTML][HTML] Adverse events, side effects and complications in mesenchymal stromal cell-based therapies

DS Baranovskii, ID Klabukov… - Stem Cell …, 2022 - ncbi.nlm.nih.gov
Numerous clinical studies have shown a wide clinical potential of mesenchymal stromal
cells (MSCs) application. However, recent experience has accumulated numerous reports of …

Intra-articular mesenchymal stem cell injection for knee osteoarthritis: mechanisms and clinical evidence

P Wei, R Bao - International Journal of Molecular Sciences, 2022 - mdpi.com
Knee osteoarthritis presents higher incidences than other joints, with increased prevalence
during aging. It is a progressive process and may eventually lead to disability. Mesenchymal …

[HTML][HTML] Mesenchymal stem cells in knee osteoarthritis treatment: a systematic review and meta-analysis

Y Song, J Zhang, H Xu, Z Lin, H Chang, W Liu… - Journal of orthopaedic …, 2020 - Elsevier
Objective Stem cells are considered to be one of the greatest potential treatments to cure
degenerative diseases. Stem cells injection for knee osteoarthritis is still a relatively new …

Clinical trials with mesenchymal stem cell therapies for osteoarthritis: challenges in the regeneration of articular cartilage

DC Carneiro, LT Araújo, GC Santos… - International Journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a whole-joint disease primarily characterized by the deterioration of
hyaline cartilage. Current treatments include microfracture and chondrocyte implantation as …