Acute kidney injury in the critically ill: an updated review on pathophysiology and management

P Pickkers, M Darmon, E Hoste, M Joannidis… - Intensive care …, 2021 - Springer
Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only
affects acute morbidity and mortality, but also a patient's long-term prognosis. In this …

Acute kidney injury after cardiac surgery: prediction, prevention, and management

SR Cheruku, J Raphael, JA Neyra, AA Fox - Anesthesiology, 2023 - ingentaconnect.com
Acute kidney injury (AKI) is a common complication in cardiac surgery patients, with a
reported incidence of 20 to 30%. The development of AKI is associated with worse short-and …

[HTML][HTML] Harmonizing acute and chronic kidney disease definition and classification: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus …

NH Lameire, A Levin, JA Kellum, M Cheung… - Kidney international, 2021 - Elsevier
Kidney disease is an important public health problem. Both acute kidney injury (AKI) and
chronic kidney disease (CKD) have been well defined and classified leading to improved …

Designing acute kidney injury clinical trials

A Zarbock, LG Forni, M Ostermann, C Ronco… - Nature Reviews …, 2024 - nature.com
Acute kidney injury (AKI) is a common clinical condition with various causes and is
associated with increased mortality. Despite advances in supportive care, AKI increases not …

Conceptual advances and evolving terminology in acute kidney disease

JA Kellum, C Ronco, R Bellomo - Nature Reviews Nephrology, 2021 - nature.com
Over the past decade, new insights into epidemiology, pathophysiology and biomarkers
have modified our understanding of acute kidney dysfunction and damage, and their …

Renal functional reserve: from physiological phenomenon to clinical biomarker and beyond

AH Jufar, YR Lankadeva, CN May… - American Journal …, 2020 - journals.physiology.org
Glomerular filtration rate (GFR) is acutely increased following a high-protein meal or
systemic infusion of amino acids. The mechanisms underlying this renal functional response …

[HTML][HTML] The impact of acute kidney injury by serum creatinine or urine output criteria on major adverse kidney events in cardiac surgery patients

P Priyanka, A Zarbock, J Izawa, TG Gleason… - The Journal of thoracic …, 2021 - Elsevier
Objectives Oliguria after cardiac surgery remains of uncertain clinical significance.
Therefore, we investigated the relationship of acute kidney injury severity across urine …

Utility of biomarkers for sepsis-associated acute kidney injury staging

L Molinari, G Del Rio-Pertuz, A Smith… - JAMA network …, 2022 - jamanetwork.com
Importance The 23rd Acute Disease Quality Initiative (ADQI-23) consensus conference
proposed a framework to integrate biomarkers into the staging of acute kidney injury (AKI). It …

Use of cell cycle arrest biomarkers in conjunction with classical markers of acute kidney injury

M Joannidis, LG Forni, M Haase, J Koyner… - Critical Care …, 2019 - journals.lww.com
Objectives: Decreased urine output and/or increased serum creatinine may herald the
development of acute kidney injury or reflect normal physiology. In this secondary analysis …

[HTML][HTML] Urinary EGF and MCP-1 and risk of CKD after cardiac surgery

S Menez, W Ju, R Menon, DG Moledina, HT Philbrook… - Jci Insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Assessment of chronic kidney disease (CKD) risk after acute kidney injury
(AKI) is based on limited markers primarily reflecting glomerular function. We evaluated …