Landscape of cellular bioeffects triggered by ultrasound-induced sonoporation

D Przystupski, M Ussowicz - International journal of molecular sciences, 2022 - mdpi.com
Sonoporation is the process of transient pore formation in the cell membrane triggered by
ultrasound (US). Numerous studies have provided us with firm evidence that sonoporation …

Lytic release of cellular ATP: Physiological relevance and therapeutic applications

R Grygorczyk, F Boudreault, O Ponomarchuk, JJ Tan… - Life, 2021 - mdpi.com
The lytic release of ATP due to cell and tissue injury constitutes an important source of
extracellular nucleotides and may have physiological and pathophysiological roles by …

[HTML][HTML] Barrier-breaking effects of ultrasonic cavitation for drug delivery and biomarker release

Y Hu, J Wei, Y Shen, S Chen, X Chen - Ultrasonics Sonochemistry, 2023 - Elsevier
Recently, emerging evidence has demonstrated that cavitation actually creates important
bidirectional channels on biological barriers for both intratumoral drug delivery and …

Nanobubble-mediated cancer cell sonoporation using low-frequency ultrasound

M Bismuth, M Eck, T Ilovitsh - Nanoscale, 2023 - pubs.rsc.org
Ultrasound insonation of microbubbles can form transient pores in cell membranes that
enable the delivery of non-permeable extracellular molecules to the cells. Reducing the size …

[HTML][HTML] Formulation and characterisation of drug-loaded antibubbles for image-guided and ultrasound-triggered drug delivery

S Kotopoulis, C Lam, R Haugse, S Snipstad… - Ultrasonics …, 2022 - Elsevier
The aim of this study was to develop high load-capacity antibubbles that can be visualized
using diagnostic ultrasound and the encapsulated drug can be released and delivered …

Genome-wide analysis of ribosomal protein GhRPS6 and its role in cotton Verticillium wilt resistance

D Zhu, X Zhang, J Zhou, Y Wu, X Zhang… - International journal of …, 2021 - mdpi.com
Verticillium wilt is threatening the world's cotton production. The pathogenic fungus
Verticillium dahliae can survive in the soil in the form of microsclerotia for a long time …

[HTML][HTML] Calcium ion delivery by microbubble-assisted sonoporation stimulates cell death in human gastrointestinal cancer cells

D Przystupski, D Baczyńska, J Rossowska… - Biomedicine & …, 2024 - Elsevier
Ultrasound-mediated cell membrane permeabilization–sonoporation, enhances drug
delivery directly to tumor sites while reducing systemic side effects. The potential of …

Novel anticancer strategies

H Bousbaa - Pharmaceutics, 2021 - mdpi.com
Cancer incidence and mortality continue to increase rapidly worldwide. Owing to the
dynamic, rapid, and adaptive nature of cancer progression, side effects and resistance …

Real-time spatiotemporal characterization of mechanics and sonoporation of acoustic droplet vaporization in acoustically responsive scaffolds

M Aliabouzar, BA Abeid, OD Kripfgans… - Applied Physics …, 2023 - pubs.aip.org
Phase-shift droplets provide a flexible and dynamic platform for therapeutic and diagnostic
applications of ultrasound. The spatiotemporal response of phase-shift droplets to focused …

Ultrasound and nanomedicine for cancer-targeted drug delivery: screening, cellular mechanisms and therapeutic opportunities

CH Li, YC Chang, M Hsiao, MH Chan - Pharmaceutics, 2022 - mdpi.com
Cancer is a disease characterized by abnormal cell growth. According to a report published
by the World Health Organization (WHO), cancer is the second leading cause of death …