Electrospun fiber scaffolds for engineering glial cell behavior to promote neural regeneration

DL Puhl, JL Funnell, DW Nelson, MK Gottipati… - Bioengineering, 2020 - mdpi.com
Electrospinning is a fabrication technique used to produce nano-or micro-diameter fibers to
generate biocompatible, biodegradable scaffolds for tissue engineering applications …

Assessing the combination of magnetic field stimulation, iron oxide nanoparticles, and aligned electrospun fibers for promoting neurite outgrowth from dorsal root …

JL Funnell, AM Ziemba, JF Nowak, H Awada… - Acta biomaterialia, 2021 - Elsevier
Magnetic fiber composites combining superparamagnetic iron oxide nanoparticles (SPIONs)
and electrospun fibers have shown promise in tissue engineering fields. Controlled grafting …

Heparin‐hyaluronic acid nanofibers for growth factor sequestration in spinal cord repair

EA Mays, SS Kallakuri… - Journal of Biomedical …, 2020 - Wiley Online Library
Growth factor (GF) delivery is a common strategy for spinal cord injury repair, however, GF
degradation can impede long‐term therapies. GF sequestration via heparin is known to …

Poly-l-lactic acid-co-poly(pentadecalactone) Electrospun Fibers Result in Greater Neurite Outgrowth of Chick Dorsal Root Ganglia in Vitro Compared to Poly-l-lactic …

AM Ziemba, KP Lane, IM San Segundo… - ACS Biomaterials …, 2018 - ACS Publications
Electrospun poly-l-lactic acid (PLLA) fiber scaffolds are used to direct axonal extension in
neural engineering models. We aimed to improve the efficacy of these fibers in promoting …

Lactonic Sophorolipid Increases Surface Wettability of Poly-l-lactic Acid Electrospun Fibers

AM Ziemba, KP Lane, B Balouch… - ACS Applied Bio …, 2019 - ACS Publications
The hydrophobicity of electrospun poly-l-lactic acid (PLLA) fibers hinders their integration
with surrounding tissue for a variety of applications. In this study, we increased PLLA fiber …

Multivariate analysis reveals topography dependent relationships amongst neurite morphological features from dorsal root ganglia neurons

DW Nelson, DL Puhl, JL Funnell… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. Nerve guidance scaffolds containing anisotropic architectures provide
topographical cues to direct regenerating axons through an injury site to reconnect the …

Enzyme-Mediated Nerve Growth Factor Release from Nanofibers Using Gelatin Microspheres

EA Mays, EB Ellis, Z Hussain, P Parajuli… - … Engineering Part A, 2023 - liebertpub.com
Spinal cord injury is a complex environment, with many conflicting growth factors present at
different times throughout the injury timeline. Delivery of multiple growth factors has received …

Magnetic electrospun fibers for neural regeneration applications

J Funnell - 2023 - search.proquest.com
Nervous system damage caused by physical trauma or degenerative diseases can result in
loss of sensory and motor function for patients. Biomaterial interventions have shown …

[图书][B] Spatiotemporal Release Of Growth Factors In A Biomaterial-Focused Organotypic Spinal Cord Injury Model

E Mays - 2020 - search.proquest.com
Over 17,000 people per year in the United States sustain a spinal cord injury (SCI) for which
there is no gold standard of care and life-long complications. SCI is a complex wound …

[PDF][PDF] Electrospun Fiber Scaffolds for Engineering Glial Cell Behavior to Promote Neural Regeneration. Bioengineering 2021, 8, 4

DL Puhl, JL Funnell, DW Nelson, MK Gottipati… - 2020 - pdfs.semanticscholar.org
Electrospinning is a fabrication technique used to produce nano-or micro-diameter fibers to
generate biocompatible, biodegradable scaffolds for tissue engineering applications …