IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …

Psoriasis is a frequent chronic inflammatory skin disease, nowadays considered a major
global health problem. Several new drugs, targeting the IL-23/IL-17A pathway, have been …

The cytokines of the interleukin 17 (IL-17) family play a central role in the control of
infections, especially extracellular fungi. Conversely, if unrestrained, these inflammatory …

IL-25, also known as IL-17E, is a unique cytokine of the IL-17 family. Indeed, IL-25
exclusively was shown to strongly induce expression of the cytokines associated with type 2 …

Abstract The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and
recently, all of its related receptors have been discovered. IL-17 was first discovered …

Psoriasis is a chronic inflammatory skin pathology of autoimmune origin and unknown
etiology. There are various therapies for treating it, including a wide range of …

In times of targeted therapies, innovative therapeutics become tools to further unravel the
pathogenesis of the treated disease, thus influencing current pathogenetic concepts. Based …

Psoriatic arthritis (PsA) is a heterogeneous chronic inflammatory arthritis associated with
psoriasis, which may manifest with different domains such as dactylitis, enthesitis, synovitis …

Abstract Interleukin-25 (IL-25), also known as IL-17E, is a cytokine belonging to the IL-17
family. IL-25 is abundantly expressed by Th2 cells and various kinds of epithelial cells. IL-25 …

Twenty to thirty percent of psoriasis (Pso) patients will develop psoriatic arthritis (PsA).
Detection of Pso patients that are (at risk for) developing PsA is essential to prevent …