Modeling and prediction of flow-induced hemolysis: a review
Despite decades of research related to hemolysis, the accuracy of prediction algorithms for
complex flows leaves much to be desired. Fundamental questions remain about how …
complex flows leaves much to be desired. Fundamental questions remain about how …
Turbulent flow promotes cleavage of VWF (von Willebrand factor) by ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type-1 motif, member 13)
Objective—Acquired von Willebrand syndrome is defined by excessive cleavage of the VWF
(von Willebrand Factor) and is associated with impaired primary hemostasis and severe …
(von Willebrand Factor) and is associated with impaired primary hemostasis and severe …
FDA benchmark medical device flow models for CFD validation
Computational fluid dynamics (CFD) is increasingly being used to develop blood-contacting
medical devices. However, the lack of standardized methods for validating CFD simulations …
medical devices. However, the lack of standardized methods for validating CFD simulations …
[HTML][HTML] An in vitro evaluation of turbulence after transcatheter aortic valve implantation
Background This study aimed at assessment of post-transcatheter aortic valve (TAV)
replacement hemodynamics and turbulence when a same-size SAPIEN 3 (Edwards …
replacement hemodynamics and turbulence when a same-size SAPIEN 3 (Edwards …
Three-dimensional microfluidic tape-paper-based sensing device for blood total bilirubin measurement in jaundiced neonates
More than 60% newborns experience hyperbilirubinemia and jaundice within the initial
week after birth due to the accumulation of total bilirubin in blood. Left untreated high levels …
week after birth due to the accumulation of total bilirubin in blood. Left untreated high levels …
Ex vivo biomechanical characterization of syringe-needle ejections for intracerebral cell delivery
Intracerebral implantation of cell suspensions is finding its clinical translation with
encouraging results in patients with stroke. However, the survival of cells in the brain …
encouraging results in patients with stroke. However, the survival of cells in the brain …
Hemodynamic performance and thrombogenic properties of a superhydrophobic bileaflet mechanical heart valve
In this study, we explore how blood-material interactions and hemodynamics are impacted
by rendering a clinical quality 25 mm St. Jude Medical Bileaflet mechanical heart valve …
by rendering a clinical quality 25 mm St. Jude Medical Bileaflet mechanical heart valve …
Hemolysis associated with Impella heart pump positioning: in vitro hemolysis testing and computational fluid dynamics modeling
N Roberts, U Chandrasekaran, S Das… - … journal of artificial …, 2020 - journals.sagepub.com
Introduction: Short-term mechanical circulatory support devices provide temporary
hemodynamic support in heart failure and are increasingly used to enable recovery or as a …
hemodynamic support in heart failure and are increasingly used to enable recovery or as a …
Experimental assessment of flow fields associated with heart valve prostheses using particle image velocimetry (PIV): recommendations for best practices
V Raghav, S Sastry, N Saikrishnan - Cardiovascular engineering and …, 2018 - Springer
Experimental flow field characterization is a critical component of the assessment of the
hemolytic and thrombogenic potential of heart valve substitutes, thus it is important to identify …
hemolytic and thrombogenic potential of heart valve substitutes, thus it is important to identify …
On the representation of effective stress for computing hemolysis
Hemolysis is a major concern in blood-circulating devices, which arises due to
hydrodynamic loading on red blood cells from ambient flow environment. Hemolysis …
hydrodynamic loading on red blood cells from ambient flow environment. Hemolysis …