A three-step framework for programming pattern formation

NS Scholes, M Isalan - Current opinion in chemical biology, 2017 - Elsevier
Highlights•Synthetic engineering of pattern formation is an essential step towards
regenerative medicine.•A three-step framework commonly underpins engineering …

The BulkECexplorer compiles endothelial bulk transcriptomes to predict functional versus leaky transcription

JT Brash, G Diez-Pinel, C Colletto… - Nature cardiovascular …, 2024 - nature.com
Transcriptomic data can be mined to understand the molecular activity of cell types. Yet,
functional genes may remain undetected in RNA sequencing (RNA-seq) experiments for …

[图书][B] Systems biology of cell signaling: recurring themes and quantitative models

J Ferrell - 2021 - taylorfrancis.com
How can we understand the complexity of genes, RNAs, and proteins and the associated
regulatory networks? One approach is to look for recurring types of dynamical behavior …

Traction microscopy with integrated microfluidics: responses of the multi-cellular island to gradients of HGF

H Jang, J Kim, JH Shin, JJ Fredberg, CY Park, Y Park - Lab on a Chip, 2019 - pubs.rsc.org
Collective cellular migration plays a central role in development, regeneration, and
metastasis. In these processes, mechanical interactions between cells are fundamental but …

Synthetic Morphogenesis: introducing IEEE journal readers to programming living mammalian cells to make structures

JA Davies - Proceedings of the IEEE, 2022 - ieeexplore.ieee.org
Synthetic morphogenesis is a new engineering discipline, in which cells are genetically
engineered to make designed shapes and structures. At least in this early phase of the field …

Transient Turing patterns in a morphogenetic model

N Guisoni, L Diambra - Frontiers in Physics, 2022 - frontiersin.org
One of the most surprising mechanisms to explain the symmetry breaking phenomenon
linked to pattern formation is known as Turing instabilities. These patterns are self …

Linear‐no‐threshold default assumptions are unwarranted for cytotoxic endpoints independently triggered by ultrasensitive molecular switches

KT Bogen - Risk Analysis, 2017 - Wiley Online Library
Crump's response in this issue to my critique of linear‐no‐threshold (LNT) default
assumptions for noncancer and nongenotoxic cancer risks (Risk Analysis 2016; 36 (3): 589 …

Engineering ultrasensivity and differential diffusion to build spatial patterns in a 3D mammalian cell culture system

VR Senthivel - 2017 - tdx.cat
Engineering self-organised spatial patterns based on reaction-diffusion models can be the
stepping stone for tissue engineering. Previous reports based on both theoretical and …