Cellular responses to widespread DNA replication stress
JA Nickoloff, AS Jaiswal, N Sharma… - International journal of …, 2023 - mdpi.com
Replicative DNA polymerases are blocked by nearly all types of DNA damage. The resulting
DNA replication stress threatens genome stability. DNA replication stress is also caused by …
DNA replication stress threatens genome stability. DNA replication stress is also caused by …
Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCA mutant cancer cells
N Ramakrishnan, TM Weaver, LN Aubuchon… - Nature …, 2024 - nature.com
Clinical success with poly (ADP-ribose) polymerase inhibitors (PARPi) is impeded by
inevitable resistance and associated cytotoxicity. Depletion of Amplified in Liver Cancer 1 …
inevitable resistance and associated cytotoxicity. Depletion of Amplified in Liver Cancer 1 …
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells
BRCA1-deficient cells have increased IRE1 RNase, which degrades multiple microRNAs.
Reconstituting expression of one of these, miR-4638–5p, resulted in synthetic lethality in …
Reconstituting expression of one of these, miR-4638–5p, resulted in synthetic lethality in …
Super-enhancer-associated EEPD1 facilitates EMT-mediated metastasis by regulating the PI3K/AKT/mTOR pathway in gastric cancer
Y Jin, Y Xia, H Du, T Xiang, B Lan, S Wei, H Li… - Biochemical and …, 2023 - Elsevier
This study focused on exploring the mechanism of the EMT mediated by endonuclease/
exonuclease/phosphatase family domain-containing 1 (EEPD1) in gastric cancer …
exonuclease/phosphatase family domain-containing 1 (EEPD1) in gastric cancer …
Genome-wide detection of selection signatures in Jianli pigs reveals novel cis-regulatory haplotype in EDNRB associated with two-end black coat color
Z Xu, J Wu, Y Zhang, M Qiao, J Zhou, Y Feng, Z Li… - BMC genomics, 2024 - Springer
Background Jianli pig, a renowned indigenous breed in China, has the characteristics of a
two-end black (TEB) coat color, excellent meat quality, strong adaptability and increased …
two-end black (TEB) coat color, excellent meat quality, strong adaptability and increased …
[HTML][HTML] Colibactin Exerts Androgen-dependent and-independent Effects on Prostate Cancer
R Agrawal, S Al-Hiyari, R Hugh-White… - European Urology …, 2024 - Elsevier
Background and objective The etiology of prostate cancer (PC) is multifactorial and poorly
understood. It has been suggested that colibactin-producing Escherichia coli positive for the …
understood. It has been suggested that colibactin-producing Escherichia coli positive for the …
[HTML][HTML] EEPD1 attenuates radiation-induced cardiac hypertrophy and apoptosis by degrading FOXO3A in cardiomyocytes: Effect of EEPD1 on radiation induced …
K Yu, X Su, T Zhou, X Cai… - Acta Biochimica et …, 2024 - pmc.ncbi.nlm.nih.gov
Radiation-induced heart disease (RIHD) is a severe delayed complication of thoracic
irradiation (IR). Endonuclease/exonuclease/phosphatase family domain-containing 1 …
irradiation (IR). Endonuclease/exonuclease/phosphatase family domain-containing 1 …
Genome-wide detection of selection signatures in Jianli pigs reveals novel cis-regulatory haplotype for two-end black coat color
Z Xu, J Wu, Y Zhang, M Qiao, J Zhou, Y Feng, Z Li… - 2023 - researchsquare.com
Background: Jianli pig, a renowned indigenous breed in China, has the characteristics of a
two-end black (TEB) coat color, excellent meat quality, strong adaptability and increased …
two-end black (TEB) coat color, excellent meat quality, strong adaptability and increased …
[图书][B] Glaciers retreat, frogs advance: rapid adaptation, genetic drift, and infection dynamics during the climate-driven range expansion of an Andean frog
EC Steigerwald - 2023 - search.proquest.com
All over the world, species are shifting their geographic distributions in response to climate
change. We know from studies of other range expansion and contraction scenarios—like …
change. We know from studies of other range expansion and contraction scenarios—like …