Until recently, the development of new human adjuvants was held back by a poor
understanding of their mechanisms of action. The field was revolutionized by the discovery …

The aging process results in multiple traceable footprints, which can be quantified and used
to estimate an organism's age. Examples of such aging biomarkers include epigenetic …

There is a growing body of evidence that links epigenetic modifications to type 2 diabetes.
Researchers have more recently investigated effects of commonly used medications …

Building evolutionarily appropriate baseline models for natural populations is not only
important for answering fundamental questions in population genetics—including …

Postpartum depression (PPD) affects 1 in 7 women and has negative mental health
consequences for both mother and child. However, the precise biological mechanisms …

DNA is naturally dynamic and can self-assemble into alternative secondary structures
including the intercalated motif (i-motif), a four-stranded structure formed in cytosine-rich …

Cancer immunotherapy has emerged as a promising strategy to treat cancer patients.
Among the wide range of immunological approaches, cancer vaccines have been …

Epigenetics studies the heritable modifications of genome expression that do not affect the
nucleotide sequence. Epigenetic modifications can be divided into: DNA methylation …

Abstract Changes in DNA methylation with age are observed across the tree of life. The
stereotypical nature of these changes can be modeled to produce epigenetic clocks capable …

Gastric cancer (GC) is one of the most common causes of cancer‐related death in the world,
with multiple genetic and epigenetic alterations involved in disease development. CYLD …