▪ Abstract DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects
mismatches generated during DNA replication and escape proofreading. MMR proteins also …

DNA mismatch repair (MMR) is an important DNA repair pathway that plays critical roles in
DNA replication fidelity, mutation avoidance and genome stability, all of which contribute …

US10207240B2 - Methods and microfluidic devices for the manipulation of droplets in high
fidelity polynucleotide assembly - Google Patents US10207240B2 - Methods and microfluidic …

Meiotic crossovers (COs) generate genetic diversity and are critical for the correct
completion of meiosis in most species. Their occurrence is tightly constrained but the …

Convergent studies demonstrated that p53 regulates homologous recombination (HR)
independently of its classic tumour-suppressor functions in transcriptionally transactivating …

The generation of protective antibodies requires somatic hypermutation (SHM) and class-
switch recombination (CSR) of immunoglobulin genes. Here we show that mice mutant for …

DNA mismatch repair (MMR) safeguards the integrity of the genome. In its role in
postreplicative repair, this repair pathway corrects base–base and insertion/deletion (I/D) …

DNA G-quadruplexes (G4s) are known to be an integral part of the complex regulatory
systems in both normal and pathological cells. At the same time, the ability of G4s to impede …

The inactivation of the DNA mismah repair (MMR) system, which is associated with the
predisposition to the hereditary non-polyposis colorectal cancer (HNPCC), has also been …

The mismatch repair (MMR) system promotes genomic fidelity by repairing base-base
mismatches, insertion-deletion loops and heterologies generated during DNA replication …