Beneficial effects of Ginkgo biloba leaf extract on inflammatory markers: A systematic review and meta‐analysis of the clinical trials

SN Mousavi, M Hosseinikia… - Phytotherapy …, 2022 - Wiley Online Library
The beneficial effects of Ginkgo biloba on cardio‐metabolic markers have been reported.
However, its effect on inflammation is not assessed in any meta‐analysis. We performed a …

Carnosic acid attenuates AβOs-induced apoptosis and synaptic impairment via regulating NMDAR2B and its downstream cascades in SH-SY5Y cells

W Liu, Y Li, Y Li, L Xu, J Jia - Molecular Neurobiology, 2023 - Springer
Neuronal death and synaptic loss are principal pathological features of Alzheimer's disease
(AD). Amyloid beta oligomers (AβOs) constitute the main neurotoxin underscoring AD …

[HTML][HTML] KCa-Related Neurological Disorders: Phenotypic Spectrum and Therapeutic Indications

A Zahra, R Liu, W Han, H Meng, Q Wang… - Current …, 2023 - ncbi.nlm.nih.gov
Although potassium channelopathies have been linked to a wide range of neurological
conditions, the underlying pathogenic mechanism is not always clear, and a systematic …

Nitronyl Nitroxide Ameliorates Hypobaric Hypoxia-Induced Cognitive Impairment in Mice by Suppressing the Oxidative Stress, Inflammatory Response and Apoptosis

L Jing, Q Da, S Zhang, J Zhang, H Ma, H Luo - Neurochemical Research, 2024 - Springer
Abundant investigations have shown that hypobaric hypoxia (HH) causes cognitive
impairment, mostly attributed to oxidative stress, inflammation, and apoptosis. HPN (4 …

Roles of nucleus accumbens shell small-conductance calcium-activated potassium channels in the conditioned fear freezing

M Zhang, Y Luo, J Wang, Y Sun, B Xie, L Zhang… - Journal of Psychiatric …, 2023 - Elsevier
Background Posttraumatic stress disorder (PTSD), a psychiatric disorder caused by stressful
events, is characterized by long-lasting fear memory. The nucleus accumbens shell (NAcS) …

Protecting effects of 4-octyl itaconate on neonatal hypoxic-ischemic encephalopathy via Nrf2 pathway in astrocytes

Y Yang, Y Li, W Yang, X Yang, M Luo, L Qin… - Journal of …, 2024 - Springer
Background Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the most common
neurological problems occurring in the perinatal period. However, there still is not a …

Sirtuin 6 ameliorates arthritis through modulating cyclic AMP-responsive element binding protein/CCN1/cyclooxygenase 2 pathway in osteoblasts

SK Lin, HW Wang, CT Shun, CN Yang… - Journal of Bone and …, 2023 - Springer
Introduction CCN1 is an immediate-early gene product pivotal for arthritis progression. We
have previously shown that sirtuin 6 (SIRT6) inhibited hypoxia-induced CCN1 expression in …

[HTML][HTML] OL-FS13 Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting miR-21-3p Expression

N Liu, Y Fan, Y Li, Y Zhang, J Li, Y Wang… - Current …, 2023 - ncbi.nlm.nih.gov
Background OL-FS13, a neuroprotective peptide derived from Odorrana livida, can alleviate
cerebral ischemia-reperfusion (CI/R) injury, although the specific underlying mechanism …

Investigation of the underlying mechanism of Buyang Huanwu decoction in ischemic stroke by integrating systems pharmacology-proteomics and in vivo experiments

W Liao, P Wang, Y He, Z Liu, L Wang - Fitoterapia, 2024 - Elsevier
Abstract Buyang Huanwu Decoction (BHD) has been effective in treating ischemic stroke
(IS). However, its mechanism of action remains unclear. The study intended to explore the …

Screening of prolyl hydroxylase 2 inhibitors based on quantitative strategy of peptides

Y Zhang, S Nsanzamahoro, CB Wang, WF Wang… - … of Chromatography A, 2022 - Elsevier
Abstract Prolyl hydroxylase 2 (PHD2) is a key oxygen receptor regulating oxygen
homeostasis in human body, and it is one of the important targets for drug research and …