Oxidative stress in liver pathophysiology and disease

A Allameh, R Niayesh-Mehr, A Aliarab, G Sebastiani… - Antioxidants, 2023 - mdpi.com
The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Immune responses in the liver

P Kubes, C Jenne - Annual review of immunology, 2018 - annualreviews.org
The liver is a key, frontline immune tissue. Ideally positioned to detect pathogens entering
the body via the gut, the liver appears designed to detect, capture, and clear bacteria …

Hepatocellular carcinoma: etiology and current and future drugs

A Jindal, A Thadi, K Shailubhai - Journal of clinical and experimental …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is swiftly increasing in prevalence globally with a high
mortality rate. The progression of HCC in patients is induced with advanced fibrosis, mainly …

Collagen 1A1 (COL1A1) is a reliable biomarker and putative therapeutic target for hepatocellular carcinogenesis and metastasis

HP Ma, HL Chang, OA Bamodu, VK Yadav, TY Huang… - Cancers, 2019 - mdpi.com
Increasing evidence shows that hepatocellular carcinoma (HCC) is a principal cause of
cancer-related mortality globally, especially among Asian and African populations. Collagen …

Viral oncology: molecular biology and pathogenesis

UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …

Radiation-induced liver disease and modern radiotherapy

EJ Koay, D Owen, P Das - Seminars in radiation oncology, 2018 - Elsevier
Modern radiotherapy techniques have enabled high focal doses of radiation to be delivered
to patients with primary and secondary malignancies of the liver. The current clinical practice …

Cancer stem cells in hepatocellular carcinoma: an overview and promising therapeutic strategies

N Wang, S Wang, MY Li, B Hu, L Liu… - … in medical oncology, 2018 - journals.sagepub.com
The poor clinical outcome of hepatocellular carcinoma (HCC) patients is ascribed to the
resistance of HCC cells to traditional treatments and tumor recurrence after curative …

[HTML][HTML] Serum biomarkers and ultrasensitive biosensors for diagnosis of early-stage hepatocellular carcinoma

LDS Lapitan Jr, M Pietrzak, M Krawczyk… - Sensors and Actuators B …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) was the third leading cause of cancer-related death
globally in 2020. The treatment of the disease is complex, with a high possibility of disease …

[HTML][HTML] Viral hepatitis and hepatocellular carcinoma: From molecular pathways to the role of clinical surveillance and antiviral treatment

L Stella, F Santopaolo, A Gasbarrini… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a global health challenge. Due to the high prevalence in
low-income countries, hepatitis B virus (HBV) and hepatitis C virus infections remain the …

A key mRNA-miRNA-lncRNA competing endogenous RNA triple sub-network linked to diagnosis and prognosis of hepatocellular carcinoma

J Zhang, W Lou - Frontiers in oncology, 2020 - frontiersin.org
Growing evidence has illustrated critical roles of competing endogenous RNA (ceRNA)
regulatory network in human cancers including hepatocellular carcinoma. In this study, we …