The diagnosis of autism: From Kanner to DSM-III to DSM-5 and beyond

NE Rosen, C Lord, FR Volkmar - Journal of autism and developmental …, 2021 - Springer
In this paper we review the impact of DSM-III and its successors on the field of autism—both
in terms of clinical work and research. We summarize the events leading up to the inclusion …

Getting to the cores of autism

LM Iakoucheva, AR Muotri, J Sebat - Cell, 2019 - cell.com
The genetic architecture of autism spectrum disorder (ASD) is itself a diverse allelic
spectrum that consists of rare de novo or inherited variants in hundreds of genes and …

Molecular and network-level mechanisms explaining individual differences in autism spectrum disorder

AM Buch, PE Vértes, J Seidlitz, SH Kim… - Nature …, 2023 - nature.com
The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

The association between theory of mind, executive function, and the symptoms of autism spectrum disorder

CRG Jones, E Simonoff, G Baird, A Pickles… - Autism …, 2018 - Wiley Online Library
It has been strongly argued that atypical cognitive processes in autism spectrum disorder
(ASD) contribute to the expression of behavioural symptoms. Comprehensive investigation …

Decreased spontaneous attention to social scenes in 6-month-old infants later diagnosed with autism spectrum disorders

K Chawarska, S Macari, F Shic - Biological psychiatry, 2013 - Elsevier
Background The ability to spontaneously attend to the social overtures and activities of
others is essential for the development of social cognition and communication. This ability is …

[HTML][HTML] Mechanisms of facial emotion recognition in autism spectrum disorders: Insights from eye tracking and electroencephalography

MH Black, NTM Chen, KK Iyer, OV Lipp, S Bölte… - Neuroscience & …, 2017 - Elsevier
While behavioural difficulties in facial emotion recognition (FER) have been observed in
individuals with Autism Spectrum Disorder (ASD), behavioural studies alone are not suited …

DSM-5 and autism spectrum disorders (ASDs): an opportunity for identifying ASD subtypes

R Grzadzinski, M Huerta, C Lord - Molecular autism, 2013 - Springer
The heterogeneous clinical presentations of individuals with autism spectrum disorders
(ASDs) poses a significant challenge for sample characterization and limits the …

Prospective longitudinal studies of infant siblings of children with autism: Lessons learned and future directions

P Szatmari, K Chawarska, G Dawson… - Journal of the American …, 2016 - Elsevier
Objective The objectives of this review are to highlight the impact of the first decade of high-
risk (HR) infant sibling work in autism spectrum disorder (ASD) and to identify potential …

Developmental trajectories of symptom severity and adaptive functioning in an inception cohort of preschool children with autism spectrum disorder

P Szatmari, S Georgiades, E Duku, TA Bennett… - JAMA …, 2015 - jamanetwork.com
Importance Symptom severity and adaptive functioning are fundamental domains of the
autism spectrum disorder (ASD) phenotype. To date, the longitudinal association between …

[HTML][HTML] Validation strategies for subtypes in psychiatry: A systematic review of research on autism spectrum disorder

JAA van Rentergem, MK Deserno, HM Geurts - Clinical Psychology …, 2021 - Elsevier
Heterogeneity within autism spectrum disorder (ASD) is recognized as a challenge to both
biological and psychological research, as well as clinical practice. To reduce unexplained …