The development of novel compounds, hydrazones has shown that they possess a wide
variety of biological activities viz. antimicrobial, anticonvulsant, antidepressant, anti …

Malaria has emerged as a major health problem worldwide after the appearance of resistant
strains of Plasmodium falciparum to the most of antimalarial drugs. The development of …

As a part of ongoing studies in developing new potent antimicrobial agents, a novel
synthesis of 2-cyano-N-(1-(3-oxo-3H-benzo [f] chromen-2-yl) ethylidene) acetohydrazide (3) …

Background: Hydrazone and its azomethine (-NHN= CH-) derivatives are widely reported for
their immense pharmacological potential. They have also been reported to possess potent …

A small library of 36 new glycohybrids of phenylhydrazono-indolinones was synthesized
employing glycosylated 1, 2, 3-triazolyl-methyl-indoline-2, 3-diones and different …

Haem is believed to be the target of some of the historically most important antimalarial
drugs, most notably chloroquine. This target is almost ideal as haem is host-derived and the …

Use of cyanoacetohydrazides as precursors in reactions leading to construction of
heterocycles is reviewed. In addition to some common heterocyclic compounds, synthesis of …

The hydrazide-hydrazone derivative 1 was formed through the reaction of cyanoacetic acid
hydrazide with 2-acetylfuran. Compound 1 underwent a series of hetrocyclization reactions …

Background Despite noticeable improvement in anti-malarial treatment, rapid growth of
resistant malaria strains points out the need for continuous development of novel anti …

Synthesis of 2-cyano-N-((2-methoxynaphthalen-1-yl) methylene)-acetohydrazide (3) and its
use as a key intermediate for the synthesis of some new heterocyclic compounds such as …