Oxytocin, neural plasticity, and social behavior

RC Froemke, LJ Young - Annual Review of Neuroscience, 2021 - annualreviews.org
Oxytocin regulates parturition, lactation, parental nurturing, and many other social behaviors
in both sexes. The circuit mechanisms by which oxytocin modulates social behavior are …

Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

[HTML][HTML] An expanded arsenal of immune systems that protect bacteria from phages

A Millman, S Melamed, A Leavitt, S Doron… - Cell host & …, 2022 - cell.com
Bacterial anti-phage systems are frequently clustered in microbial genomes, forming
defense islands. This property enabled the recent discovery of multiple defense systems …

Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons

Y Tang, D Benusiglio, A Lefevre, L Hilfiger… - Nature …, 2020 - nature.com
Oxytocin (OT) is a great facilitator of social life but, although its effects on socially relevant
brain regions have been extensively studied, OT neuron activity during actual social …

A hypothalamic novelty signal modulates hippocampal memory

S Chen, L He, AJY Huang, R Boehringer, V Robert… - Nature, 2020 - nature.com
The ability to recognize information that is incongruous with previous experience is critical
for survival. Novelty signals have therefore evolved in the mammalian brain to enhance …

[HTML][HTML] Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

[HTML][HTML] The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation

CR Lee, A Chen, KM Tye - Cell, 2021 - cell.com
Social homeostasis is the ability of individuals to detect the quantity and quality of social
contact, compare it to an established set-point in a command center, and adjust the effort …

Perturbation of maternal gut microbiota in mice during a critical perinatal window influences early neurobehavioral outcomes in offspring

C Morel, IM Sanchez, Y Cherifi, N Chartrel… - Neuropharmacology, 2023 - Elsevier
The gut microbiota is increasingly recognized as a key environmental factor that shapes host
development and physiology, including neural circuits formation and function. Concurrently …

[HTML][HTML] Reconstruction of the hypothalamo-neurohypophysial system and functional dissection of magnocellular oxytocin neurons in the brain

B Zhang, L Qiu, W Xiao, H Ni, L Chen, F Wang, W Mai… - Neuron, 2021 - cell.com
The hypothalamo-neurohypophysial system (HNS), comprising hypothalamic magnocellular
neuroendocrine cells (MNCs) and the neurohypophysis, plays a pivotal role in regulating …