Evolutionary studies suggest that 200–250 million years ago an aphid ancestor was infected
with a free-living eubacterium. The latter became established within aphid cells. Host and …

Chlamydiae are medically important bacteria responsible for a wide range of human
infections and diseases. Repeated episodes of infection promote chronic inflammation …

Structural modeling of macromolecular complexes greatly benefits from interactive
visualization capabilities. Here we present the integration of several modeling tools into …

Members of the conserved Hsp70 chaperone family are assumed to constitute a main
cellular system for the prevention and the amelioration of stress‐induced protein damage …

Bacteriophage T4 is the most well-studied member of Myoviridae, the most complex family of
tailed phages. T4 assembly is divided into three independent pathways: the head, the tail …

Both chlamydial and human heat shock protein 60s (HSP 60), which colocalize in human
atheroma, may contribute to inflammation during atherogenesis. We tested the hypothesis …

Heat-shock regulation of bacteria functions with the release of a set of heat-shock proteins to
replace rapidly damaged proteins. Sigma-32 essential for cell growth at high temperature is …

The Saccharomyces cerevisiae APE1 gene product, aminopeptidase I (API), is a soluble
hydrolase that has been shown to be localized to the vacuole. API lacks a standard signal …

Mining the emerging abundance of microbial genome sequences for hypotheses is an
exciting prospect of “functional genomics”. At the forefront of this effort, we compared the …

DegP is a heat-shock inducible periplasmic protease in Escherichia coli. Unlike the
cytoplasmic heat shock proteins, DegP is not transcriptionally regulated by the classical heat …