D-Amino acid oxidase: structure, catalytic mechanism, and practical application
VI Tishkov, SV Khoronenkova - Biochemistry (Moscow), 2005 - Springer
D-Amino acid oxidase (DAAO) is a FAD-dependent enzyme that plays an important role in
microbial metabolism, utilization of endogenous D-amino acids, regulation of the nervous …
microbial metabolism, utilization of endogenous D-amino acids, regulation of the nervous …
Bacterial d-amino acid oxidases: Recent findings and future perspectives
S Takahashi, K Abe, Y Kera - Bioengineered, 2015 - Taylor & Francis
D-Amino acid oxidase (DAO) is a flavin enzyme that catalyzes the oxidative deamination of d-
amino acids. This enzyme has been studied extensively both biochemically and structurally …
amino acids. This enzyme has been studied extensively both biochemically and structurally …
Correlation Analysis of Key Residue Sites between Computational-Aided Design Thermostability d-Amino Acid Oxidase and Ancestral Enzymes
LY Wang, H Tang, JQ Zhao, MN Wang… - Journal of Agricultural …, 2023 - ACS Publications
The d-amino acid oxidase (DAAO) from Rhodotorula taiwanensis has proven to have great
potential for applications due to its excellent catalytic kinetic parameters. However, its poor …
potential for applications due to its excellent catalytic kinetic parameters. However, its poor …
Engineering the properties of D-amino acid oxidases by a rational and a directed evolution approach
D-amino acid oxidase (DAAO) is a FAD-containing flavoprotein that dehydrogenates the D-
isomer of amino acids to the corresponding imino acids, coupled with the reduction of FAD …
isomer of amino acids to the corresponding imino acids, coupled with the reduction of FAD …
Antimicrobial d-amino acid oxidase-derived peptides specify gut microbiota
The flavoenzyme d-amino acid oxidase (DAAO) is deputed to the degradation of d-
enantiomers of amino acids. DAAO plays various relevant physiological roles in different …
enantiomers of amino acids. DAAO plays various relevant physiological roles in different …
Modulating d-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all d-amino acids by directed evolution
Recent research on the flavoenzyme d-amino acid oxidase from Rhodotorula gracilis
(RgDAAO) has revealed new, intriguing properties of this catalyst and offers novel …
(RgDAAO) has revealed new, intriguing properties of this catalyst and offers novel …
Expression in Escherichia coli and in vitro refolding of the human protein pLG72
Recently, genes coding for pLG72 and d-amino acid oxidase have been related to
schizophrenia, a widespread psychiatric disorder that affects about 1% of population. pLG72 …
schizophrenia, a widespread psychiatric disorder that affects about 1% of population. pLG72 …
Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase
L Caldinelli, S Iametti, A Barbiroli, F Bonomi… - Journal of Biological …, 2004 - ASBMB
The flavoenzyme d-amino acid oxidase (DAAO) from Rhodotorula gracilis is a peroxisomal
enzyme and a prototypical member of the glutathione reductase family of flavoproteins …
enzyme and a prototypical member of the glutathione reductase family of flavoproteins …
The role of cofactor binding in tryptophan accessibility and conformational stability of His-tagged D-amino acid oxidase from Trigonopsis variabilis
d-amino acid oxidase from Trigonopsis variabilis (TvDAAO) is a flavoenzyme with high
biotechnological and industrial interest. The overexpression and purification of the …
biotechnological and industrial interest. The overexpression and purification of the …
Subunit fusion of two yeast d-amino acid oxidases enhances their thermostability and resistance to H2O2
SJ Wang, CY Yu, CK Lee, MK Chern, IC Kuan - Biotechnology letters, 2008 - Springer
Abstract d-Amino acid oxidases from Rhodosporidium toruloides and Trigonopsis variabilis
(RtDAO and TvDAO) are both yeast homodimeric flavoenzymes. Two of their cDNA genes …
(RtDAO and TvDAO) are both yeast homodimeric flavoenzymes. Two of their cDNA genes …