Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most
of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane …

Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Cell membranes contain hundreds of different proteins and lipids in an asymmetric
arrangement. Our current understanding of the detailed organization of cell membranes …

Lipid rafts are small, dynamic membrane areas characterized by the clustering of selected
membrane lipids as the result of the spontaneous separation of glycolipids, sphingolipids …

Cognitive processes, particularly learning and memory, are crucial brain mechanisms
mediating the successful adaptation of individuals to constantly changing environmental …

Gangliosides are glycolipids in which an oligosaccharide headgroup containing one or
more sialic acids is connected to a ceramide. Gangliosides reside in the outer leaflet of the …

Sphingolipids are structural components in the plasma membranes of eukaryotic cells. Their
metabolism produces bioactive signaling molecules that modulate fundamental cellular …

G protein‐coupled receptors (GPCRs) are cell membrane associated signaling hubs that
orchestrate a multitude of cellular functions upon binding to a diverse variety of extracellular …

Gprotein-coupled receptors (GPCRs) are seven transmembrane receptors that mediate a
large number of cellular responses and are important drug targets. One of the current …