[HTML][HTML] An overview of bioinformatics tools for epitope prediction: implications on vaccine development
RE Soria-Guerra, R Nieto-Gomez… - Journal of biomedical …, 2015 - Elsevier
Exploitation of recombinant DNA and sequencing technologies has led to a new concept in
vaccination in which isolated epitopes, capable of stimulating a specific immune response …
vaccination in which isolated epitopes, capable of stimulating a specific immune response …
Reverse vaccinology: developing vaccines in the era of genomics
A Sette, R Rappuoli - Immunity, 2010 - cell.com
The sequence of microbial genomes made all potential antigens of each pathogen available
for vaccine development. This increased by orders of magnitude potential vaccine targets in …
for vaccine development. This increased by orders of magnitude potential vaccine targets in …
Identification of vaccine targets in pathogens and design of a vaccine using computational approaches
Antigen identification is an important step in the vaccine development process.
Computational approaches including deep learning systems can play an important role in …
Computational approaches including deep learning systems can play an important role in …
Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches
J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …
Immunoinformatics-guided designing of epitope-based subunit vaccine from Pilus assembly protein of Acinetobacter baumannii bacteria
Acinetobacter baumannii, a prominent pathogen responsible for chronic infections in the
blood, urinary tract, and lungs, has a high mortality due to its virulence and limited …
blood, urinary tract, and lungs, has a high mortality due to its virulence and limited …
Designing an efficient multi-epitope peptide vaccine against Vibrio cholerae via combined immunoinformatics and protein interaction based approaches
Cholera continues to be a major global health concern. Among different Vibrio cholerae
strains, only O1 and O139 cause acute diarrheal diseases that are related to epidemic and …
strains, only O1 and O139 cause acute diarrheal diseases that are related to epidemic and …
Designing a multi-epitope vaccine to provoke the robust immune response against influenza A H7N9
H Tarrahimofrad, S Rahimnahal, J Zamani… - Scientific Reports, 2021 - nature.com
A new strain of Influenza A Virus (IAV), so-called" H7N9 Avian Influenza", is the first strain of
this virus in which a human is infected by transmitting the N9 of influenza virus. Although …
this virus in which a human is infected by transmitting the N9 of influenza virus. Although …
Emerging vaccine informatics
Vaccine informatics is an emerging research area that focuses on development and
applications of bioinformatics methods that can be used to facilitate every aspect of the …
applications of bioinformatics methods that can be used to facilitate every aspect of the …
The key role of genomics in modern vaccine and drug design for emerging infectious diseases
It can be argued that the arrival of the “genomics era” has significantly shifted the paradigm
of vaccine and therapeutics development from microbiological to sequence-based …
of vaccine and therapeutics development from microbiological to sequence-based …
In silico designing and immunoinformatics analysis of a novel peptide vaccine against metallo-beta-lactamase (VIM and IMP) variants
The rapid spread of acquired metallo-beta-lactamases (MBLs) among gram negative
pathogens is becoming a global concern. Improper use of broad-spectrum antibiotics can …
pathogens is becoming a global concern. Improper use of broad-spectrum antibiotics can …