Hyaluronic acid: A review on its biology, aspects of drug delivery, route of administrations and a special emphasis on its approved marketed products and recent …

S Vasvani, P Kulkarni, D Rawtani - International journal of biological …, 2020 - Elsevier
Hyaluronic acid (HA) is a large non-sulphated glycosaminoglycan that is an important
component of extracellular matrix (ECM) and a biodegradable polymer. Due to a variation in …

The content and size of hyaluronan in biological fluids and tissues

MK Cowman, HG Lee, KL Schwertfeger… - Frontiers in …, 2015 - frontiersin.org
Hyaluronan is a simple repeating disaccharide polymer, synthesized at the cell surface by
integral membrane synthases. The repeating sequence is perfectly homogeneous, and is …

Co-delivery of cisplatin and doxorubicin by covalently conjugating with polyamidoamine dendrimer for enhanced synergistic cancer therapy

XL Guo, XX Kang, YQ Wang, XJ Zhang, CJ Li, Y Liu… - Acta biomaterialia, 2019 - Elsevier
Because of the synergistic effects of drugs and minimal drug dose for cancer therapy,
combination chemotherapy is frequently used in the clinic. In this study, hyaluronic acid …

The extracellular matrix in epithelial ovarian cancer–a piece of a puzzle

A Cho, VM Howell, EK Colvin - Frontiers in oncology, 2015 - frontiersin.org
Epithelial ovarian cancer is the fifth leading cause of cancer-related deaths in women and
the most lethal gynecological malignancy. Extracellular matrix (ECM) is an integral …

Hyaluronan and hyaluronan fragments

MK Cowman - Advances in carbohydrate chemistry and biochemistry, 2017 - Elsevier
The glycosaminoglycan hyaluronan (HA) is a key component of the microenvironment
surrounding cells. In healthy tissues, HA molecules have extremely high molecular mass …

Antifungal polymeric materials and nanocomposites

W Ntow-Boahene, D Cook, L Good - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Rising global populations due to medicinal advancements increases the patient population
susceptible to superficial and severe fungal infections. Fungi often implicated in these …

A novel portable immuno-device for the recognition of lymphatic vessel endothelial hyaluronan receptor-1 biomarker using GQD–AgNPrs conductive ink stabilized on …

A Mobed, F Kohansal, S Dolati, M Hasanzadeh - RSC advances, 2023 - pubs.rsc.org
Lymphatic vessel endothelium expresses various lymphatic marker molecules. LYVE-1, the
lymphatic vessel endothelial hyaluronan (HA) receptor, a 322-residue protein belonging to …

Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG‐6 expression in a tumor type‐specific manner

FM Spinelli, DL Vitale, A Icardi, I Caon… - The FEBS …, 2019 - Wiley Online Library
Hyaluronan is a glycosaminoglycan normally present in the extracellular matrix in most
tissues. Hyaluronan is a crucial player in many processes associated with cancer, such as …

Hyaluronic acid nanohydrogel loaded with quercetin alone or in combination to a macrolide derivative of rapamycin RAD001 (Everolimus) as a new treatment for …

V Quagliariello, RV Iaffaioli, E Armenia… - Journal of cellular …, 2017 - Wiley Online Library
The aim of this study is based on the evaluation of anticancer, anti‐inflammatory activities,
and cellular uptake of hyaluronic acid nanohydrogel of quercetin tested alone and in …

Plasma hyaluronic acid level as a prognostic and monitoring marker of metastatic breast cancer

C Peng, M Wallwiener, A Rudolph… - … journal of cancer, 2016 - Wiley Online Library
Conventional tumor markers have limited value for prognostication and treatment monitoring
in metastatic breast cancer (MBC) patients and novel circulating tumor markers therefore …