Simulating human digestion: developing our knowledge to create healthier and more sustainable foods

A Mackie, AI Mulet-Cabero, A Torcello-Gómez - Food & function, 2020 - pubs.rsc.org
The gold standard for nutrition studies is clinical trials but they are expensive and variable,
and do not always provide the mechanistic information required, hence the increased use of …

[HTML][HTML] Implementing New Approach Methodologies (NAMs) in food safety assessments: Strategic objectives and actions taken by the European Food Safety …

I Cattaneo, MC Astuto, M Binaglia, Y Devos… - Trends in Food Science …, 2023 - Elsevier
Abstract Background New Approach Methodologies (NAMs) comprise in silico and in vitro
methods applied as alternative to animal testing. Even though NAMs are already fully …

INFOGEST static in vitro simulation of gastrointestinal food digestion

A Brodkorb, L Egger, M Alminger, P Alvito… - Nature protocols, 2019 - nature.com
Developing a mechanistic understanding of the impact of food structure and composition on
human health has increasingly involved simulating digestion in the upper gastrointestinal …

Myths and realities about genetically modified food: A risk-benefit analysis

A Vega Rodríguez, C Rodríguez-Oramas… - Applied Sciences, 2022 - mdpi.com
The development and consumption of genetically modified (GM) crops are surrounded by
controversy. According to proponents, only molecular biology approaches and genetic …

Biotechnological advances to improve abiotic stress tolerance in crops

MA Villalobos-López, A Arroyo-Becerra… - International Journal of …, 2022 - mdpi.com
The major challenges that agriculture is facing in the twenty-first century are increasing
droughts, water scarcity, flooding, poorer soils, and extreme temperatures due to climate …

[HTML][HTML] Stability of allergens

J Pekar, D Ret, E Untersmayr - Molecular immunology, 2018 - Elsevier
For proteins to cause IgE-mediated allergic reactions, several common characteristics have
to be defined, including small molecular size, solubility and stability to changing pH levels …

Guidance on the scientific requirements for an application for authorisation of a novel food in the context of Regulation (EU) 2015/2283

EFSA Panel on Nutrition, Novel Foods and Food … - EFSA …, 2024 - Wiley Online Library
Abstract The European Commission requested EFSA to update the scientific guidance for
the preparation of applications for authorisation of novel foods, previously developed …

Intended and unintended consequences of genetically modified crops–myth, fact and/or manageable outcomes?

JR Caradus - New Zealand Journal of Agricultural Research, 2023 - Taylor & Francis
Food and feed has been produced from genetically modified (GM) crops for 25 years. It is
timely to review whether this technology has globally delivered the expected benefits and …

Safety assessment of genetically modified feed: is there any difference from food?

PA Giraldo, H Shinozuka, GC Spangenberg… - Frontiers in plant …, 2019 - frontiersin.org
Food security is one of major concerns for the growing global population. Modern
agricultural biotechnologies, such as genetic modification, are a possible solution through …

[HTML][HTML] The relevance of a digestibility evaluation in the allergenicity risk assessment of novel proteins. Opinion of a joint initiative of COST action ImpARAS and …

K Verhoeckx, KL Bøgh, D Dupont, L Egger… - Food and Chemical …, 2019 - Elsevier
The current allergenicity assessment of novel proteins is based on the EFSA GMO guidance.
Recently, EFSA launched a new guidance document on allergenicity assessment of GM …