Serotonin reuptake inhibitor antidepressants, including selective serotonin reuptake
inhibitors (SSRIs; ie, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and …

This paper explores the transformative role of pharmacists in integrating pharmacogenomics
into clinical practice. Pharmacogenomics, the study of genetic influences on drug response …

Introduction Reporting and sharing pharmacogenetic test results across clinical laboratories
and electronic health records is a crucial step toward the implementation of clinical …

Objective: The objective of this review is to summarize the state of the art of clinical decision
support (CDS) circa 1990, review progress in the 25 year interval from that time, and provide …

Clinical implementation of pharmacogenomics (PGx) leads to personalized medicine, which
improves the efficacy, safety, and cost-effectiveness of treatments. Although PGx-based …

Genomic medicine attempts to build individualized strategies for diagnostic or therapeutic
decision-making by utilizing patients' genomic information. Big Data analytics uncovers …

We describe here the design and initial implementation of the eMERGE‐PGx project.
eMERGE‐PGx, a partnership of the Electronic Medical Records and Genomics Network and …

The antiretroviral protease inhibitor atazanavir inhibits hepatic uridine diphosphate
glucuronosyltransferase (UGT) 1A1, thereby preventing the glucuronidation and elimination …

Purpose Existing pharmacogenomic informatics models, key implementation steps, and
emerging resources to facilitate the development of pharmacogenomic clinical decision …

Numerous pharmacogenetic clinical guidelines and recommendations have been
published, but barriers have hindered the clinical implementation of pharmacogenetics. The …