This document aims to provide practical guidance for the assessment and management of
patients with thrombocytopenia, with a particular focus on immune thrombocytopenia (ITP) …

Beyond haemostasis, platelets have emerged as versatile effectors of the immune response.
The contribution of platelets in inflammation, tissue integrity and defence against infections …

Background Sepsis is a major risk factor for the development of thrombocytopenia, but few
studies have specifically evaluated prognostic importance of thrombocytopenia in patients …

Background Although thrombocytopenia in the intensive care unit (ICU) is associated with a
poorer outcome, the precise relationship between the time course of platelet counts and the …

Measurements and Main Results The prevalence of intensive care unit-acquired
thrombocytopenia (platelet count,< 150.0/nL) was 64 of 145 patients (44%). Intensive care …

The platelet, a fascinating anucleate cell, is critically important for haemostasis. Platelet
transfusions have greatly reduced the incidence of major haemorrhagic complications …

The many comorbidities in the severely ill patient also make thrombocytopenia very common
(∼ 40%) in intensive care unit patients. The risk of bleeding is high with severe …

Background Thrombocytopenia is common in ICU patients. The objective of this study was to
evaluate possible links between declining platelet counts early in the ICU stay and survival …

A low platelet count is a frequently encountered haematological abnormality in patients
treated in intensive treatment units (ITU s). Although severe thrombocytopenia (platelet …

Thrombocytopenia is common among patients admitted to the intensive care unit (ICU).
Multiple pathophysiological mechanisms may contribute, including thrombin-mediated …