Heat shock proteins (Hsps) are conserved molecules whose main role is to facilitate folding
of other proteins. Most Hsps are generally stress-inducible as they play a particularly …

Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

Chronic inflammatory mediators exert pleiotropic effects in the development of cancer. On
the one hand, inflammation favors carcinogenesis, malignant transformation, tumor growth …

Recent studies have initiated a paradigm shift in the understanding of the function of heat
shock proteins (HSP). It is now clear that HSP can and do exit mammalian cells, interact with …

Peptides bound or linked to heat-shock proteins (HSPs) of microbial or mammalian origin
have been shown to elicit potent antigen-specific immunity. Some members of the HSP …

Heat shock proteins (HSPs) such as HSP 60 (Hsp60), Hsp70, Hsp90, and gp96, have been
reported to play important roles in antigen presentation and cross-presentation, activation of …

Immune responses to heat shock proteins (Hsp) develop in virtually all inflammatory
diseases; however, the significance of such responses is only now becoming clear. In …

Extracellular stress proteins including heat shock proteins (Hsp) and glucose regulated
proteins (Grp) are emerging as important mediators of intercellular signaling and transport …

Extensive work in the last 10 years has suggested that heat shock proteins (HSPs) may be
potent activators of the innate immune system. It has been reported that Hsp60, Hsp70 …

Background Triple-negative breast cancer (TNBC) exhibit characteristics quite distinct from
other kinds of breast cancer, presenting as an aggressive disease--recurring and …