The dermis is primarily composed of the extracellular matrix (ECM) and fibroblasts. During
the aging process, the dermis undergoes significant changes. Collagen, which is a major …

Collagen-based supplements have become a keystone in the management of the ageing
process, with proven ability to repair skin damage, bestowing a youthful and healthy …

Organoids are 3D cell culture systems that mimic some of the structural and functional
characteristics of an organ. Organoid cultures provide the opportunity to study organ-level …

The emergence of phytosome nanotechnology has a potential impact in the field of drug
delivery and could revolutionize the current state of topical bioactive phytochemicals …

Despite the wide recognition of larger artery stiffness as a highly clinically relevant and
independent prognostic biomarker, it has yet be incorporated into routine clinical practice …

Collagen-peptide supplementation could be an effective remedy to improve hydration,
elasticity, and wrinkling in human skin. The aim of this study was to conduct a double-blind …

Human tissues must be elastic, much like other materials that work under continuous loads
without losing functionality. The elasticity of tissues is provided by elastin, a unique protein of …

Ageing of human skin may result from both the passage of time (intrinsic ageing) and from
cumulative exposure to external influences (extrinsic ageing) such as ultraviolet radiation …

The extracellular matrix (ECM) is a complex network of macromolecules surrounding cells
providing structural support and stability to tissues. The understanding of the ECM and the …

The quality of life of ageing populations is increasingly determined by age-related changes
to the mechanical properties of numerous biological tissues. Degradation and mechanical …