Charcot-Marie-Tooth (CMT) is the most prevalent category of inherited neuropathy. The most
common inheritance pattern is autosomal dominant, though there also are X-linked and …

Cancer is a hyperproliferative disorder that is usually treated by chemotherapeutic agents
that are toxic not only to tumor cells but also to normal cells, so these agents produce major …

Summary Charcot–Marie–Tooth disease is the most common inherited neuromuscular
disorder. There have been substantial advances in elucidating the molecular bases of this …

Neurodegenerative diseases result in the loss of functional neurons and synapses. Although
future stem cell therapies offer some hope, current treatments for most of these diseases are …

Abstract Background Diabetic Sensorimotor Polyneuropathy (DSPN) is a common
complication of diabetes mellitus. Curcumin is the most important ingredient found in …

Insect meals are novel and potentially sustainable protein sources. The objectives of this
study were to determine the chemical composition and standardized amino acid digestibility …

OBJECTIVE—Endoplasmic reticulum (ER) stress–induced apoptosis may be a common
cause of cell attrition in diseases characterized by misfolding and oligomerisation of …

Apoptosis is a highly regulated mechanism by which cells undergo cell death in an active
way. As one of the most challenging tasks concerning cancer is to induce apoptosis in …

Inherited neuropathies known as Charcot-Marie-Tooth (CMT) disease are genetically
heterogeneous disorders affecting the peripheral nerves, causing significant and slowly …

Recent human genetic studies have consistently shown that mutations in the same gene or
same genomic region can increase the risk of a broad range of complex neuropsychiatric …