The role of retinal dysfunction in myopia development

Y Huang, X Chen, J Zhuang, K Yu - Cellular and Molecular Neurobiology, 2023 - Springer
Myopia is a refractive disorder arising from a mismatch between refractive power and
relatively long axial length of the eye. With its dramatically increasing prevalence, myopia …

Omics in myopia

ET Grochowski, K Pietrowska, T Kowalczyk… - Journal of Clinical …, 2020 - mdpi.com
Myopia is a globally emerging issue, with multiple medical and socio-economic burdens and
no well-established causal treatment thus far. A better insight into altered biochemical …

[图书][B] Vitagenes in avian biology and poultry health

PF Surai - 2020 - wageningenacademic.com
Commercial poultry production is associated with various types of stress leading to decrease
of productive and reproductive performance and compromised health of growing chickens …

Proteomics analysis of N-methyl-d-aspartate-induced cell death in retinal and optic nerves

L Suo, W Dai, X Chen, X Qin, G Li, S Song, D Zhang… - Journal of …, 2022 - Elsevier
This study aimed to comprehensively understand the proteomic characteristics and
modulation of the neural microenvironment with N-methyl-d-aspartate (NMDA)-induced …

RNA-seq and GSEA identifies suppression of ligand-gated chloride efflux channels as the major gene pathway contributing to form deprivation myopia

LG Vocale, S Crewther, N Riddell, NE Hall, M Murphy… - Scientific reports, 2021 - nature.com
Currently there is no consensus regarding the aetiology of the excessive ocular volume that
characterizes high myopia. Thus, we aimed to test whether the gene pathways identified by …

Top-down proteomics and comparative 2D-DIGE analysis

K Ohlendieck - Difference Gel Electrophoresis: Methods and Protocols, 2022 - Springer
The combination of large-scale protein separation techniques, sophisticated mass
spectrometry, and systems bioinformatics has led to the establishment of proteomics as a …

[HTML][HTML] Establishment and comprehensive characterization of a novel dark-reared zebrafish model for myopia studies

J Xie, PT Goodbourn, BV Bui, PR Jusuf - Experimental Eye Research, 2024 - Elsevier
Myopia is predicted to impact approximately 5 billion people by 2050, necessitating
mechanistic understanding of its development. Myopia results from dysregulated genetic …

Dynamic BMP gene expression regulation in chick RPE during recovery from short term optical defocus and form-deprivation

Y Zhang, Q Zhu, W Song, GM Chuang, D Sun… - Plos one, 2024 - journals.plos.org
Purpose This study investigated the differential gene expression of BMPs in chick retinal
pigment epithelium (RPE) during recovery from short term exposure to optical defocus and …

Contralateral effect in progression and recovery of lens‐induced myopia in mice

Z Ma, H Jeong, Y Yang, X Jiang, S Ikeda… - Ophthalmic and …, 2023 - Wiley Online Library
Purpose Apart from genetic factors, recent animal studies on myopia have focused on
localised mechanisms. In this study, we aimed to examine the contralateral effects of …

Mass spectrometry‐based retina proteomics

L Prokai, K Zaman… - Mass spectrometry reviews, 2023 - Wiley Online Library
A subfield of neuroproteomics, retina proteomics has experienced a transformative growth
since its inception due to methodological advances in enabling chemical, biochemical, and …