Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …

Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60%
of all cases), associated with loss of memory (in particular episodic memory), cognitive …

Increased plasma homocysteine is a risk factor for several pathological disorders. The
present review focused on the role of homocysteine (Hcy) in different population groups …

Background Alzheimer disease (AD) patients are at risk of nutritional insufficiencies because
of physiological and psychological factors. Nutritional compounds are postulated to play a …

There are many reasons for reviewing the neurology of vitamin-B12 and folic-acid
deficiencies together, including the intimate relation between the metabolism of the two …

Context Blood levels of homocysteine may be increased in Alzheimer disease (AD) and
hyperhomocysteinemia may contribute to disease pathophysiology by vascular and direct …

Mild to moderate hyperhomocysteinemia is a risk factor for neurodegenerative diseases.
Human studies suggest that homocysteine (Hcy) plays a role in brain damage, cognitive and …

The chemistry of Alzheimer’s disease - Chemical Society Reviews (RSC Publishing) DOI:10.1039/B807980N
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/B807980N …

Parkinson's disease (PD) is one of the common progressive neurodegenerative disorders
with several motor and non-motor symptoms. Most of the motor symptoms may appear at a …

Background B vitamins in the one-carbon metabolism pathway (folate, vitamin B 6, and
vitamin B 12) have been implicated in DNA methylation, and their deficiency may contribute …