Abstract 3D bioprinting is a revolutionary technology capable of replicating native tissue and
organ microenvironments by precisely placing cells into 3D structures using bioinks …

Protection of transplanted cells from the host immune system using immunoisolation
technology will be important in realizing the full potential of cell-based therapeutics …

The cytoarchitecture of human islets has been examined, focusing on cellular associations
that provide the anatomical framework for paracrine interactions. By using confocal …

Advanced imaging techniques have become a valuable tool in the study of complex
biological processes at the cellular level in biomedical research. Here, we introduce a new …

Transplantation of islets of Langerhans represents a viable therapeutic approach for the
treatment of type 1 diabetes. Unfortunately, transplanted islets are susceptible to allogeneic …

Organ-on-a-chip platforms serve as cost-efficient testbeds for screening pharmaceutical
agents, mimicking natural physiology, and studying disease. In the field of diabetes, the …

Background. Transplantation of pancreatic islets for the treatment of type 1 diabetes allows
for physiologic glycemic control and insulin-independence when sufficient islets are …

It has indeed been a distinct honor to be the recipient of the 2002 Outstanding Scientific
Achievement Award, and I was happy to accept it, on behalf of the entire islet transplant field …

Transplantation of islets of Langerhans is a potential cure for type 1 diabetes, but its success
is hampered by destruction of the islets. The data presented herein suggest that the active …

Insufficient insulin secretion is a key component of both type 1 and type 2 diabetes. Since
insulin is released by the islets of Langerhans, obtaining viable and functional islets is …