Spinal cord injury (SCI) is a complex tissue injury resulting in permanent and degenerating
damage to the central nervous system (CNS). Detrimental cellular processes occur after SCI …

Cell therapies for neurological disorders are entering the clinic and present unique
challenges and opportunities compared with conventional medicines. They have the …

Organoids with region-specific architecture could facilitate the repair of injuries of the central
nervous system. Here we show that human astrocytes can be directly reprogrammed into …

Spinal cord injury (SCI) causes tremendous harm to a patient's physical, mental, and
financial health. Moreover, recovery of SCI is affected by many factors, inflammation is one …

Cell transplantation therapy using human induced pluripotent stem cell-derived neural
stem/progenitor cells (hiPSC-NS/PCs) is a new therapeutic strategy for spinal cord injury …

Central nervous system (CNS) injuries, including stroke, traumatic brain injury, and spinal
cord injury, are leading causes of long-term disability. It is estimated that more than half of …

Spinal cord injury (SCI) is a complex tissue injury that results in a wide range of physical
deficits, including permanent or progressive disabilities of sensory, motor and autonomic …

Spinal cord injury is a condition in which the parenchyma of the spinal cord is damaged by
trauma or various diseases. While rapid progress has been made in regenerative medicine …

Stem cell therapy holds immense potential as a viable treatment for a widespread range of
intractable disorders. As the safety of stem cell transplantation having been demonstrated in …

Expectations for neural stem/progenitor cell (NS/PC) transplantation as a treatment for spinal
cord injury (SCI) are increasing. However, whether and how grafted cells are incorporated …