Plants are autotrophic and photosynthetic organisms that both produce and consume
sugars. Soluble sugars are highly sensitive to environmental stresses, which act on the …

First conceptualized as a mechanism for the mitochondrial transport of long‐chain fatty acids
in the early 1960s, the carnitine palmitoyltransferase (CPT) system has since come to be …

The mechanisms by which higher plants recognize and respond to sugars are largely
unknown. Here, we present evidence that the first enzyme in the hexose assimilation …

Nutrient metabolism was examined with regard to insulin secretion in purified rat islet beta-
and non-beta-cells, beta-cell lines, and hepatocytes. Lactate dehydrogenase (LDH) activity …

Sucrose is required for plant growth and development. The sugar status of plant cells is
sensed by sensor proteins. The signal generated by signal transduction cascades, which …

Sugar repression of photosynthetic genes is likely a central control mechanism mediating
energy homeostasis in a wide range of algae and higher plants. It overrides light activation …

Patients with the metabolic syndrome are characterized by insulin resistance, obesity and a
predisposition to hypertension, dyslipidaemia, pancreatic β-cell dysfunction, type 2 diabetes …

Previous studies in rat islets have suggested that anaplerosis plays an important role in the
regulation of pancreatic β cell function and growth. However, the relative contribution of islet …

Abbreviations: NEFA, Non-esterified fatty acids; GSIS, glucose-stimulated insulin secretion;
2-BrP, 2-bromopalmitate; 2-BrS, 2-bromostearate; LC-CoA, long chain acyl-CoA; NA …

β-Cells possess inherent mechanisms to adapt to overnutrition and the prevailing
concentrations of glucose, fatty acids, and other fuels to maintain glucose homeostasis …