Sports drug testing using complementary matrices: advantages and limitations

M Thevis, H Geyer, L Tretzel, W Schänzer - Journal of pharmaceutical and …, 2016 - Elsevier
Today, routine doping controls largely rely on testing whole blood, serum, and urine
samples. These matrices allow comprehensively covering inorganic as well as low and high …

Analytical strategies based on mass spectrometric techniques for the study of steroid metabolism

C Gomez, A Fabregat, ÓJ Pozo, J Marcos… - TrAC Trends in …, 2014 - Elsevier
Anabolic androgenic steroids (AASs) are synthetic substances derived from testosterone,
whose use in sports is prohibited. This review underlines the advantages and the drawbacks …

Use of LC-MS/MS for the open detection of steroid metabolites conjugated with glucuronic acid

A Fabregat, OJ Pozo, J Marcos, J Segura… - Analytical …, 2013 - ACS Publications
In humans, conjugation with glucuronic acid is the most important phase II metabolic
reaction of steroidal compounds. Glucuronoconjugated metabolites have been …

Simplifying and expanding analytical capabilities for various classes of doping agents by means of direct urine injection high performance liquid chromatography high …

C Görgens, S Guddat, A Thomas, P Wachsmuth… - … of Pharmaceutical and …, 2016 - Elsevier
So far, in sports drug testing compounds of different classes are processed and measured
using different screening procedures. The constantly increasing number of samples in …

A review of current chemistry, pharmacology, and regulation of endogenous anabolic steroids testosterone, boldenone, and nandrolone in horses

L Dirikolu, AF Lehner - Journal of Veterinary Pharmacology and …, 2023 - Wiley Online Library
Anabolic androgenic steroids are synthetic substances related to the male sex hormones
(androgens). These agents promote the growth of skeletal muscle (anabolic effects) and the …

Alternative long-term markers for the detection of methyltestosterone misuse

C Gómez, OJ Pozo, J Marcos, J Segura, R Ventura - Steroids, 2013 - Elsevier
Methyltestosterone (MT) is one of the most frequently detected anabolic androgenic steroids
in doping control analysis. MT misuse is commonly detected by the identification of its two …

Current LC–MS methods and procedures applied to the identification of new steroid metabolites

J Marcos, OJ Pozo - The Journal of Steroid Biochemistry and Molecular …, 2016 - Elsevier
The study of the metabolism of steroids has a long history; from the first characterizations of
the major metabolites of steroidal hormones in the pre-chromatographic era, to the latest …

A new sulphate metabolite as a long-term marker of metandienone misuse

C Gomez, OJ Pozo, L Garrostas, J Segura, R Ventura - Steroids, 2013 - Elsevier
Metandienone is one of the most frequently detected anabolic androgenic steroids in sports
drug testing. Metandienone misuse is commonly detected by monitoring different …

Trace Analysis of Five Androgens in Environmental Waters by Optimization of Enzymolysis and Solid‐Phase Extraction Ultra‐Performance Liquid Chromatography …

Y Xie, Z Gao, Y Ren - Environmental Toxicology and Chemistry, 2023 - academic.oup.com
Steroid hormones (SHs) have received widespread attention in recent years. However,
current studies of SHs have primarily focused on estrogenic substances, with androgen …

Profiling urinary sulfate metabolites with mass spectrometry

CCJ Fitzgerald, R Hedman, DR Uduwela… - Frontiers in Molecular …, 2022 - frontiersin.org
The study of urinary phase II sulfate metabolites is central to understanding the role and fate
of endogenous and exogenous compounds in biological systems. This study describes a …