[HTML][HTML] 5-Fluorouracil (5-FU) resistance and the new strategy to enhance the sensitivity against cancer: Implication of DNA repair inhibition

C Sethy, CN Kundu - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Fluorouracil (5-FU) has been an important anti-cancer drug to date. With an increase in the
knowledge of its mechanism of action, various treatment modalities have been developed …

[HTML][HTML] Strategic approaches for colon targeted drug delivery: an overview of recent advancements

SH Lee, R Bajracharya, JY Min, JW Han, BJ Park… - Pharmaceutics, 2020 - mdpi.com
Colon targeted drug delivery systems have gained a great deal of attention as potential
carriers for the local treatment of colonic diseases with reduced systemic side effects and …

[HTML][HTML] A review on drug delivery system for tumor therapy

G Liu, L Yang, G Chen, F Xu, F Yang, H Yu… - Frontiers in …, 2021 - frontiersin.org
In recent years, with the development of nanomaterials, the research of drug delivery
systems has become a new field of cancer therapy. Compared with conventional antitumor …

Current advances in chitosan nanoparticles based oral drug delivery for colorectal cancer treatment

H Choukaife, S Seyam, B Alallam… - International journal …, 2022 - Taylor & Francis
As per the WHO, colorectal cancer (CRC) caused around 935,173 deaths worldwide in 2020
in both sexes and at all ages. The available anticancer therapies including chemotherapy …

Specific surface modification of liposomes for gut targeting of food bioactive agents

T Zhang, X Xu, Y Pan, H Yang, J Han… - … Reviews in Food …, 2023 - Wiley Online Library
Liposomes have become a research hotspot in recent years as food delivery systems with
attractive properties, including the bilayer structure assembled like the cell membrane …

[HTML][HTML] 5-fluorouracil-loaded folic-acid-fabricated chitosan nanoparticles for site-targeted drug delivery cargo

S Ullah, AK Azad, A Nawaz, KU Shah, M Iqbal… - Polymers, 2022 - mdpi.com
Nanoparticles play a vital role in cancer treatment to deliver or direct the drug to the
malignant cell, avoiding the attacking of normal cells. The aim of the study is to formulate …

[HTML][HTML] Single-versus dual-targeted nanoparticles with folic acid and biotin for anticancer drug delivery

M Jurczyk, K Jelonek, M Musiał-Kulik, A Beberok… - Pharmaceutics, 2021 - mdpi.com
Cancer is one of the major causes of death worldwide and its treatment remains very
challenging. The effectiveness of cancer therapy significantly depends upon tumour-specific …

Current trends and future perspectives of nanomedicine for the management of colon cancer

S Wahab, MY Alshahrani, MF Ahmad… - European Journal of …, 2021 - Elsevier
Colon cancer (CC) kills countless people every year throughout the globe. It persists as one
of the highly lethal diseases to be treated because the overall survival rate for CC is meagre …

[HTML][HTML] Formulation strategies for folate-targeted liposomes and their biomedical applications

P Kumar, P Huo, B Liu - Pharmaceutics, 2019 - mdpi.com
The folate receptor (FR) is a tumor-associated antigen that can bind with folic acid (FA) and
its conjugates with high affinity and ingests the bound molecules inside the cell via the …

[HTML][HTML] Cabazitaxel and silibinin co-encapsulated cationic liposomes for CD44 targeted delivery: a new insight into nanomedicine based combinational …

S Mahira, N Kommineni, GM Husain, W Khan - Biomedicine & …, 2019 - Elsevier
Cancer stem cells (CSCs) are the promising targets for cancer chemotherapy that cannot be
eliminated by conventional chemotherapy. In this study cationic liposomes of cabazitaxel …