Lung cancer is the third most diagnosed cancer, but the first cause of cancer-related deaths
worldwide. This rather high death rate is due mainly to the fact that most patients are …

Evidence demonstrates that brain-derived neurotrophic factor (BDNF) has a pivotal role in
the pathogenesis of major depressive disorder (MDD). Precursor-BDNF (proBDNF) and …

DNA/RNA methylation plays an important role in lung cancer initiation and progression.
Liquid biopsy makes use of cells, nucleotides and proteins released from tumor cells into …

Telomeres play a major role in human aging and disease, especially in most cancers.
Telomere length was shortened in workers exposed to polycyclic aromatic hydrocarbons …

Background We recently reported the importance of deep learning (DL) of pelvic magnetic
resonance imaging in predicting the degree of urinary incontinence (UI) following robot …

Aim: Small single-stranded non-coding RNAs (miRNAs) play an important role in
carcinogenesis through degrading target mRNAs. However, the diagnostic value of miRNAs …

As an emerging technology, artificial intelligence has been applied to identify various
physical disorders. Here, we developed a three-layer diagnosis system for lung cancer, in …

Specific gene promoter DNA methylation is becoming a powerful epigenetic biomarker in
cancer diagnostics. Five genes (CDH1, CDKN2Ap16, RASSF1A, TERT, and WT1) were …

Coal tar pitch extract (CTPE) was carcinogenic and could cause occupational lung cancer.
Hence, we explored the changes of protein molecules during CTPE-induced malignant …

This review outlines the major trends in the investigation of circulating cell-free DNA-based
methylated markers, including key technical aspects of the circulating cell-free DNA …