Harnessing the potential of nanoengineered siRNAs carriers for target responsive glioma therapy: Recent progress and future opportunities

K Ahirwar, A Kumar, N Srivastava, SA Saraf… - International Journal of …, 2024 - Elsevier
Past scientific testimonials in the field of glioma research, the deadliest tumor among all
brain cancer types with the life span of 10-15 months after diagnosis is considered as …

[HTML][HTML] A Sequencing Overview of Malignant Peripheral Nerve Sheath Tumors: Findings and Implications for Treatment

K Xiao, K Yang, AC Hirbe - Cancers, 2025 - mdpi.com
Malignant peripheral nerve sheath tumors (MPNSTs) are rare but aggressive malignancies
with a low 5-year survival rate despite current treatments. MPNSTs frequently harbor …

[HTML][HTML] Enhancing targeted therapy by combining PI3K and AKT inhibitors with or without cisplatin or vincristine in medulloblastoma cell lines in vitro

M Lukoseviciute, E Need, M Birgersson… - Biomedicine & …, 2024 - Elsevier
Aim Despite current intensive therapy, survival rates of medulloblastoma (MB) greatly vary
according to molecular subgroup, so new therapies are needed. Recently, we showed that …

Multiparametric MRI-based machine learning system of molecular subgroups and prognosis in medulloblastoma

Z Liu, S Ren, H Zhang, Z Liao, Z Liu, X An, J Cheng… - European …, 2025 - Springer
Objectives We aimed to use artificial intelligence to accurately identify molecular subgroups
of medulloblastoma (MB), predict clinical outcomes, and incorporate deep learning-based …

[HTML][HTML] Impact of treatment and clinical characteristics on the survival of children with medulloblastoma in Mexico

V Salceda-Rivera, I Tejocote-Romero… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Methods A retrospective analysis was conducted, involving 284 patients treated at 21
pediatric oncology centers in Mexico. Results High-risk patients exhibited markedly lower …

[PDF][PDF] Use of neuroendoscopy in combination treatment of a three-year-old patient with primary disseminated medulloblastoma: a case report

JA Ashurov, G Musa, EV Kumirova, SN Margaryan… - Cureus, 2024 - cureus.com
A three-year-four-month-old boy with primary disseminated medulloblastoma M3 stage and
secondary occlusive hydrocephalus underwent an endoscopic triventriculocisternostomy …

The Management of Children with Pre-School Medulloblastoma–A Review of Four Decades of Multi-Disciplinary and Multi-Institutional Collaboration.

P Navalkele, G Dhall, JL Finlay - Medical Research Archives, 2024 - esmed.org
Background: The management and consequent survival and quality of survival for young
children with medulloblastoma have undergone substantial improvement over the last four …

Role of SHh modulation in neurogenesis and tumorigenesis

A Apostolico - 2025 - tesidottorato.depositolegale.it
The SHh pathway plays a major role in a variety of different processes, ranging from
embryogenesis to the homeostasis maintenance of adult tissues, with Central Nervous …

WHO Classification of CNS Tumors (General Principles)

O Atallah, AY Alahmed, MH Algabri, SA Saleh… - … Neuro-Oncology: In …, 2024 - Springer
This chapter delves into the structured framework of the World Health Organization (WHO)
classification of central nervous system CNS tumors. This chapter provides a systematic …

Salvage Therapies for Relapsed Shh Medulloblastoma of Early Childhood

CA Erker, M Mynarek, M Simbozel, BT Craig… - papers.ssrn.com
Background: Sonic hedgehog (SHH) medulloblastoma is the most common molecular group
of infant and early childhood medulloblastoma (iMB) and has no standard of care at relapse …