Structural, biochemical and immunochemical characterization of an acidic phospholipase A2 from Lachesis acrochorda (Viperidae: Crotalinae) venom

AM Franco-Vásquez, F Lazcano-Pérez… - Toxicon, 2024 - Elsevier
Viperids of the genus Lachesis, also known as bushmasters, are capable of injecting great
amounts of venom that cause severe envenomation incidents. Since phospholipases type A …

cDNA Cloning, Heterologous Expression, Cytotoxicity, and Inhibitory Effects of a Disintegrin from Bothrops ammodytoides Venom

H Clement, LL Corrales-García… - International Journal of …, 2023 - Springer
An mRNA transcript that codes for a Disintegrin and a Metalloprotease from a venom gland
of the viper Bothrops ammodytoides was isolated. Vector pCR® 2.1-TOPO was used to …

[HTML][HTML] Heterologous expression of four recombinant toxins from Panamanian scorpions of the genus Tityus and Centruroides for production of antivenom

MH Salazar, H Clement, LL Corrales-García… - Toxicon: X, 2022 - Elsevier
Background The development of more effective antivenoms remains a necessity for
countries where scorpionism is a public health problem. Also, the regionalization of …

Recombinant expression and antigenicity of two peptide families of neurotoxins from Androctonus sp.

S Cardoso-Arenas, H Clement, I Arenas… - Journal of Venomous …, 2022 - SciELO Brasil
Background: Scorpion neurotoxins such as those that modify the mammalian voltage-gated
sodium ion channels (Nav) are the main responsible for scorpion envenomation. Their …

Immunogenic Properties of Recombinant Enzymes from Bothrops ammodytoides towards the Generation of Neutralizing Antibodies against Its Own Venom

H Clement, LL Corrales-García, D Bolaños, G Corzo… - Toxins, 2019 - mdpi.com
Bothropic venoms contain enzymes such as metalloproteases, serine-proteases, and
phospholipases, which acting by themselves, or in synergism, are the cause of the …

Neutralization of “Chaco eagle”(Buteogallus coronatus) serum on some activities of Bothrops spp. venoms

PI Regner, MD Saggese, VC de Oliveira, LC Lanari… - Toxicon, 2022 - Elsevier
Several species of reptiles and mammals have components in their sera that can neutralize
toxic components present in snake venoms. In this manuscript, we studied the neutralizing …

Molecular cloning and characterization of a gene encoding HMG-CoA reductase involved in triterpenoids biosynthetic pathway from Sanghuangporus baumii

Z Liu, S Wang, X Xu, S Wang, T Sun… - Biotechnology & …, 2021 - Taylor & Francis
Sanghuangporus baumii (Pilát)(Zhou and Dai), a traditional Chinese medicinal fungus, has
been confirmed to produce triterpenoids, which possess a good anti-cancer effect. However …

[PDF][PDF] Purificación, caracterización y expresión recombinante de la fosfolipasa A2 miotóxica del veneno de la serpiente Bothrops pictus y su efecto sobre la viabilidad …

ADP TORRES - 2023 - researchgate.net
El envenenamiento por mordedura de serpiente (ofidismo) es un problema de salud pública
que ocurre en distintas zonas tropicales del mundo y que ha sido catalogado por la OMS …

Estudos estruturais com miotoxinas fosfolipase a2-like isoladas e recombinante da peçonha de bothrops pauloensis

BM Zamboni - 2020 - repositorio.unesp.br
A toxicidade do veneno das serpentes do gênero Bothrops é resultante da ação integrada
de várias toxinas, entre elas as fosfolipases A2 (PLA2s). Entre o grupo das PLA2s, há as …

[PDF][PDF] PROGRAMA DE MAESTRÍA Y DOCTORADO EN FILOSOFÍA FACULTAD DE FILOSOFÍA Y LETRAS INSTITUTO DE INVESTIGACIONES FILOSÓFICAS

DLAMEH EL - 2017 - academia.edu
RESUMEN GENERAL. El objetivo de este trabajo es indagar el sentido que cobran los
temas de la inmortalidad del alma y la existencia de Dios, en el marco del criticismo …