Intoxicated aggression: Do alcohol and stimulants cause dose-related aggression? A review
KPC Kuypers, RJ Verkes, W van den Brink… - European …, 2020 - Elsevier
Rationale Violence and drug use are significant public health challenges that are strongly
linked. It is known that alcohol plays a major role in the causation of unnatural deaths and …
linked. It is known that alcohol plays a major role in the causation of unnatural deaths and …
Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects
Rationale: Lisdexamfetamine is a prodrug of d-amphetamine used for the treatment of
attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is thought to have a …
attention-deficit/hyperactivity disorder (ADHD). Lisdexamfetamine is thought to have a …
PET imaging of dopamine-D2 receptor internalization in schizophrenia
Recent genetic, molecular and post-mortem studies suggest impaired dopamine (DA)-D2
receptor (D2R) trafficking in patients with schizophrenia (SZ). Imaging and preclinical …
receptor (D2R) trafficking in patients with schizophrenia (SZ). Imaging and preclinical …
Conceptualizing health behaviors as acute mood-altering agents: implications for cancer control
A massive portion of cancer burden is accounted for by a small collection of highly prevalent
cancer risk behaviors (eg, low physical activity, unhealthy diet, and tobacco use). Why …
cancer risk behaviors (eg, low physical activity, unhealthy diet, and tobacco use). Why …
Lack of consistent sex differences in d-amphetamine-induced dopamine release measured with [18F]fallypride PET
Rationale Sex differences in the dopaminergic response to psychostimulants could have
implications for drug abuse risk and other psychopathology involving the dopamine system …
implications for drug abuse risk and other psychopathology involving the dopamine system …
Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT2A receptor activation
Perception, emotion, and mood are powerfully modulated by serotonin receptor (5-HTR)
agonists including hallucinogens. The 5-HT2AR subtype has been shown to be central to …
agonists including hallucinogens. The 5-HT2AR subtype has been shown to be central to …
Variability in paralimbic dopamine signaling correlates with subjective responses to d-amphetamine
Subjective responses to psychostimulants vary, the basis of which is poorly understood,
especially in relation to possible cortical contributions. Here, we tested for relationships …
especially in relation to possible cortical contributions. Here, we tested for relationships …
Functional validation of a finding from a mouse genome‐wide association study shows that Azi2 influences the acute locomotor stimulant response to …
X Zhou, AM Barkley‐Levenson… - Genes, Brain and …, 2021 - Wiley Online Library
In a previous genome‐wide association study (GWAS) using outbred Carworth Farms White
(CFW) mice, we identified a locus that influenced the stimulant response to …
(CFW) mice, we identified a locus that influenced the stimulant response to …
Functional validation of a finding from a mouse genome-wide association study demonstrates that a mutant allele of Azi2 alters sensitivity to methamphetamine
X Zhou, A Barkley-Levenson, P Montilla-Perez… - bioRxiv, 2020 - biorxiv.org
Methamphetamine is a widely abused psychostimulant. In a previous genome-wide
association study (GWAS), we identified a locus that influenced the stimulant response to …
association study (GWAS), we identified a locus that influenced the stimulant response to …
The contribution of animal models to our understanding of addictive processes
S Schenk - The Routledge International Handbook of …, 2018 - taylorfrancis.com
This chapter discusses measurement of the efficacy and potency of a drug in terms of the
acquisition and maintenance of self-administration. Animal models provide a means for …
acquisition and maintenance of self-administration. Animal models provide a means for …