Epithelial–mesenchymal transition (EMT) is a developmental cellular process occurring
during early embryo development, including gastrulation and neural crest cell migration. It …

Dietary polyunsaturated fatty acids (PUFAs), especially omega-3 (n-3) and n-6 long-chain
(LC) PUFAs, are indispensable for the fetus' brain supplied by the placenta. Despite being …

Epithelial-to-mesenchymal transition (EMT) is a dynamic process that produces migratory
cells from epithelial precursors. However, EMT is not binary; rather it results in migratory …

Background: Bicuspid aortic valve (BAV), the most common congenital heart defect affecting
1% to 2% of the population, is a major risk factor for premature aortic valve disease and …

Neural crest cells (NCCs) are a dynamic, multipotent, vertebrate-specific population of
embryonic stem cells. These ectodermally-derived cells contribute to diverse tissue types in …

Craniofacial anomalies are among the most common of birth defects. The pathogenesis of
craniofacial anomalies frequently involves defects in the migration, proliferation, and fate of …

Neural crest cells (NCCs) are a population of multipotent cells that migrate extensively
during vertebrate development. Alterations to neural crest ontogenesis cause several …

Neural crest cells are multipotent progenitors that dynamically interpret diverse
microenvironments to migrate significant distances as a loosely associated collective and …

The gelatinases, a subgroup of the matrix metalloproteinases (MMPs) superfamily are
composed of two members; MMP2 and MMP9. They are known to degrade gelatin among …

Sensory nerves of the brainstem are mostly composed of placode-derived neurons, neural
crest-derived neurons and neural crest-derived Schwann cells. This mixed origin of cells has …