Living organisms evolve complex genetic networks to interact with the environment. Due to
the rapid development of synthetic biology, various modularized genetic parts and units …

Metabolic engineering reprograms cells to synthesize value-added products. In doing so,
endogenous genes are altered and heterologous genes can be introduced to achieve the …

Engineered RNA elements are programmable tools capable of detecting small molecules,
proteins, and nucleic acids. Predicting the behavior of these synthetic biology components …

Highlights•Outperforming microbial cell factories requires elaborate and programmable
devices.•Biosensors are engineered for dynamic control with various input signals.•CRISPR …

Engineered microbes are exciting alternatives to current diagnostics and therapeutics.
Researchers have developed a wide range of genetic tools and parts to engineer probiotic …

To overcome environmental problems caused by the use of fossil resources, microbial cell
factories have become a promising technique for the sustainable and eco-friendly …

Toehold switches are de novo designed riboregulators that contain two RNA components
interacting through linear‐linear RNA interactions, regulating the gene expression. These …

Due to the toxicity of mercury and its harmful effects on human health, it is essential to
establish a low-cost, highly sensitive and highly specific monitoring method with a wide …

Synthetic biology aims to program living bacteria cells with artificial genetic circuits for user-
defined functions, transforming them into powerful tools with numerous applications in …

Nucleic acid therapeutics (NATs) hold promise in treating undruggable diseases and are
recognized as the third major category of therapeutics in addition to small molecules and …