Inhalable particulate drug delivery systems for lung cancer therapy: Nanoparticles, microparticles, nanocomposites and nanoaggregates

HM Abdelaziz, M Gaber, MM Abd-Elwakil… - Journal of Controlled …, 2018 - Elsevier
There is progressive evolution in the use of inhalable drug delivery systems (DDSs) for lung
cancer therapy. The inhalation route offers many advantages, being non-invasive method of …

Implications of protein-and peptide-based nanoparticles as potential vehicles for anticancer drugs

AO Elzoghby, MM Elgohary, NM Kamel - Advances in protein chemistry …, 2015 - Elsevier
Protein-based nanocarriers have gained considerable attention as colloidal carrier systems
for the delivery of anticancer drugs. Protein nanocarriers possess various advantages …

Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer

SA Sabra, AO Elzoghby, SA Sheweita… - European Journal of …, 2018 - Elsevier
Protein-based micelles have shown significant potential for tumor-targeted delivery of anti-
cancer drugs. In this light, self-assembled nanocarriers based on GRAS (Generally …

Polysaccharides for the delivery of antitumor drugs

B Posocco, E Dreussi, J De Santa, G Toffoli, M Abrami… - Materials, 2015 - mdpi.com
Among the several delivery materials available so far, polysaccharides represent very
attractive molecules as they can undergo a wide range of chemical modifications, are …

Dual-targeted casein micelles as green nanomedicine for synergistic phytotherapy of hepatocellular carcinoma

MA Abdelmoneem, M Mahmoud, A Zaky… - Journal of Controlled …, 2018 - Elsevier
In recent years, green nanomedicines have made transformative difference in cancer
therapy researches. Herein, we propose dual-functionalized spray-dried casein micelles …

Novel ionically crosslinked casein nanoparticles for flutamide delivery: formulation, characterization, and in vivo pharmacokinetics

AO Elzoghby, MW Helmy, WM Samy… - International journal of …, 2013 - Taylor & Francis
A novel particulate delivery matrix based on ionically crosslinked casein (CAS)
nanoparticles was developed for controlled release of the poorly soluble anticancer drug …

Simultaneous encapsulation of dasatinib and celecoxib into caseinate micelles towards improved in vivo anti-breast cancer efficacy with reduced drug toxicity

CA Lamey, N Moussa, MW Helmy, M Haroun… - Journal of Drug Delivery …, 2023 - Elsevier
Breast cancer is the most global dominant cancer among females. Although there are
continuously growing strategies to develop new therapies, the outcomes are usually …

Phytosomal bilayer-enveloped casein micelles for codelivery of monascus yellow pigments and resveratrol to breast cancer

SW El-Far, MW Helmy, SN Khattab, AA Bekhit… - …, 2018 - Taylor & Francis
Aim: Multireservoir nanocarriers were fabricated for delivering antineoplastic drug cocktail
from herbal and fungal origin. Monascus yellow pigments (MYPs), monascin and ankaflavin …

Zein-based nanocarriers as potential natural alternatives for drug and gene delivery: focus on cancer therapy

A Elzoghby, M Freag, H Mamdouh… - Current …, 2017 - ingentaconnect.com
Protein nanocarriers possess unique merits including minimal cytotoxicity, numerous
renewable sources, and high drug-binding capability. In opposition to delivery carriers …

Novel spray-dried genipin-crosslinked casein nanoparticles for prolonged release of alfuzosin hydrochloride

AO Elzoghby, WM Samy, NA Elgindy - Pharmaceutical research, 2013 - Springer
Purpose To propose a simple method for the development of genipin-crosslinked casein
micelles as a new delivery platform for prolonged release of alfuzosin hydrochloride …