Impact of microbial metabolites on microbiota–gut–brain axis in inflammatory bowel disease

D Banfi, E Moro, A Bosi, M Bistoletti… - International journal of …, 2021 - mdpi.com
The complex bidirectional communication system existing between the gastrointestinal tract
and the brain initially termed the “gut–brain axis” and renamed the “microbiota–gut–brain …

Rates of endoscopic recurrence in postoperative Crohn's Disease based on anastomotic techniques: a systematic review and Meta-analysis

OM Nardone, G Calabrese, B Barberio… - Inflammatory Bowel …, 2024 - academic.oup.com
Abstract Background Patients with Crohn's disease (CD) after ileocolic resection may
develop an endoscopic postoperative recurrence (ePOR) that reaches 40% to 70% of …

Hyperoside ameliorates DSS-induced colitis through MKRN1-mediated regulation of PPARγ signaling and Th17/Treg balance

C Cheng, W Zhang, C Zhang, P Ji, X Wu… - Journal of agricultural …, 2021 - ACS Publications
Hyperoside (HYP), a naturally occurring flavonoid compound, exerts multiple biological
functions including myocardial protection, antiredox, and anti-inflammatory activities …

Preventive effect of pectic oligosaccharides on acute colitis model mice: modulating epithelial barrier, gut microbiota and Treg/Th17 balance

H Wang, N Liu, Z Yang, K Zhao, H Pang, K Shao… - Food & function, 2022 - pubs.rsc.org
Pectin as a dietary fiber supplement has shown emerging potential in clinical ulcerative
colitis (UC) adjuvant therapy. In this study, the preventive and prebiotic effects of …

The microbiota-gut-brain axis: Focus on the fundamental communication pathways

M Bistoletti, A Bosi, D Banfi, C Giaroni, A Baj - Progress in molecular …, 2020 - Elsevier
The existence of a bidirectional communication system termed the “gut-brain axis” linking
the gastrointestinal tract with the brain has been recognized since the nineteenth century. In …

[HTML][HTML] Preoperative Crohn's Disease Exclusion Diet and Exclusive Enteral Nutrition in Adults with Crohn's Disease: A Feasibility Randomised Controlled Trial

CL Wall, R Bensley, T Glyn, M Haines, D Rowbotham… - Nutrients, 2024 - mdpi.com
Preoperative exclusive enteral nutrition (EEN) improves nutritional status, reduces intestinal
inflammation, and likely improves surgical outcomes. Crohn's disease exclusion diet with …

[HTML][HTML] Therapeutic and immunologic effects of short-chain fatty acids in inflammatory bowel disease: a systematic review

I Ventura, M Chomon-García, F Tomás-Aguirre… - International Journal of …, 2024 - mdpi.com
Inflammatory bowel disease is a chronic condition characterized by recurrent intestinal
inflammation. Its etiopathogenesis is driven by a series of events that disrupt the mucosal …

Advances in the comprehensive management of postoperative Crohn's disease

R Battat, WJ Sandborn - Clinical Gastroenterology and Hepatology, 2022 - Elsevier
Patients with postoperative Crohn's disease are difficult to manage because of their risk of
experiencing a more severe course, multiple symptom confounders, and poor sensitivity of …

Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases

H Kayama, K Takeda - European Journal of Immunology, 2023 - Wiley Online Library
The intestinal tract harbors diverse microorganisms, host‐and microbiota‐derived
metabolites, and potentially harmful dietary antigens. The epithelial barrier separates the …

After surgically induced remission, ileal and colonic mucosa-associated microbiota predicts Crohn's disease recurrence

C Hernández-Rocha, W Turpin, K Borowski… - Clinical …, 2024 - Elsevier
Background & Aims Investigating the tissue-associated microbiota after surgically induced
remission may help to understand the mechanisms initiating intestinal inflammation in …