Cognitive control in pediatric obsessive-compulsive and anxiety disorders: brain-behavioral targets for early intervention

KD Fitzgerald, HS Schroder, R Marsh - Biological Psychiatry, 2021 - Elsevier
The DSM provides distinct criteria for obsessive-compulsive disorder (OCD) and various
types of anxiety disorders, but phenomenological overlap, high rates of comorbidity, and …

[HTML][HTML] Hyperbolic trade-off: The importance of balancing trial and subject sample sizes in neuroimaging

G Chen, DS Pine, MA Brotman, AR Smith, RW Cox… - NeuroImage, 2022 - Elsevier
Here we investigate the crucial role of trials in task-based neuroimaging from the
perspectives of statistical efficiency and condition-level generalizability. Big data initiatives …

[HTML][HTML] Trial and error: A hierarchical modeling approach to test-retest reliability

G Chen, DS Pine, MA Brotman, AR Smith, RW Cox… - NeuroImage, 2021 - Elsevier
The concept of test-retest reliability indexes the consistency of a measurement across time.
High reliability is critical for any scientific study, but specifically for the study of individual …

Threat appraisal and pediatric anxiety: Proof of concept of a Latent variable approach

RA Bernstein, AR Smith, ER Kitt… - Clinical …, 2024 - journals.sagepub.com
Elevated threat appraisal is a postulated neurodevelopmental mechanism of anxiety
disorders. However, laboratory-assessed threat appraisals are task-specific and subject to …

Neural responding during uncertain threat anticipation in pediatric anxiety

KJ Michalska, B Benson, EJ Ivie, JF Sachs… - International Journal of …, 2023 - Elsevier
Excessive fear responses to uncertain threat are a key feature of anxiety disorders (ADs),
though most mechanistic work considers adults. As ADs onset in childhood and confer risk …

Cross-sectional and longitudinal associations of anxiety and irritability with adolescents' neural responses to cognitive conflict

EM Cardinale, J Bezek, S Morales, C Filippi… - Biological Psychiatry …, 2023 - Elsevier
Background Psychiatric symptoms are commonly comorbid in childhood. The ability to
disentangle unique and shared correlates of comorbid symptoms facilitates personalized …

Behavioral inhibition and dual mechanisms of anxiety risk: Disentangling neural correlates of proactive and reactive control

EA Valadez, SV Troller‐Renfree, GA Buzzell… - JCPP …, 2021 - Wiley Online Library
Background Behavioral inhibition (BI) is a temperament style characterized by heightened
reactivity and negative affect in response to novel people and situations, and it predicts …

Amygdala functional connectivity and negative reactive temperament at age 4 months

CA Filippi, S Ravi, M Bracy, A Winkler… - Journal of the American …, 2021 - Elsevier
Objective Infant amygdala connectivity correlates with maternal reports of infant
temperament characterized by novelty-evoked distress and avoidance. However, no studies …

Overcontrol and neural response to errors in pediatric anxiety disorders

K Gilbert, MT Perino, MJ Myers, CM Sylvester - Journal of anxiety disorders, 2020 - Elsevier
Multiple risk factors that may contribute to the development and severity of pediatric anxiety
disorders, one of which is dimensional overcontrol. Overcontrol is a constellation of …

The genetic architecture of youth anxiety: a study protocol

L McAusland, CL Burton, A Bagnell, K Boylan… - BMC psychiatry, 2024 - Springer
Background Anxiety disorders are the most common psychiatric problems among Canadian
youth and typically have an onset in childhood or adolescence. They are characterized by …