The role of melanins in melanotic fungi for pathogenesis and environmental survival

HC Eisenman, EM Greer, CW McGrail - Applied microbiology and …, 2020 - Springer
Melanins provide fungi protection from environmental stressors, support their ecological
roles, and can confer virulence in pathogens. While the function, structure, and synthesis of …

Life on a leaf: the epiphyte to pathogen continuum and interplay in the phyllosphere

G Thomas, WT Kay, HN Fones - BMC biology, 2024 - Springer
Epiphytic microbes are those that live for some or all of their life cycle on the surface of plant
leaves. Leaf surfaces are a topologically complex, physicochemically heterogeneous habitat …

Effect of melanin biosynthesis inhibition on the antifungal susceptibility of chromoblastomycosis agents

D Heidrich, DM Pagani, A Koehler… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
Chromoblastomycosis (CBM) is a chronic subcutaneous infection caused by genera of
melanized fungi: Fonsecaea, Cladophialophora, Phialophora, Exophiala, and …

Melanization of Candida auris Is Associated with Alteration of Extracellular pH

DFQ Smith, NJ Mudrak, D Zamith-Miranda, L Honorato… - Journal of Fungi, 2022 - mdpi.com
Candida auris is a recently emerged global fungal pathogen, which causes life-threatening
infections, often in healthcare settings. C. auris infections are worrisome because the fungus …

Melanin and chromoblastomycosis agents: Characterization, functions, and relation with antifungals

A Koehler, D Heidrich, DM Pagani… - Journal of Basic …, 2021 - Wiley Online Library
Melanins are a diverse group of dark pigments with similar properties. In fungi, the most
studied is the dihydroxynaphtalene (DHN)‐melanin, present in several species including all …

Iron Starvation Induces Ferricrocin Production and the Reductive Iron Acquisition System in the Chromoblastomycosis Agent Cladophialophora carrionii

AM Bailão, KLP Silva, D Moraes, B Lechner, H Lindner… - Journal of Fungi, 2023 - mdpi.com
Iron is a micronutrient required by almost all living organisms. Despite being essential, the
availability of this metal is low in aerobic environments. Additionally, mammalian hosts …

Characterizing phenotype variants of Cercosporidium personatum, causal agent of peanut late leaf spot disease, their morphology, genetics and metabolites

RS Arias, EG Cantonwine, VA Orner, TE Walk… - Scientific Reports, 2025 - nature.com
Cercosporidium personatum (CP) causes peanut late leaf spot (LLS) disease with 70% yield
losses unless controlled by fungicides. CP grows slowly in culture, exhibiting variable …

Prediction of melanin content of Fonsecaea pedrosoi using Fourier transform infrared spectroscopy (FTIR) and chemometrics

A Koehler, PC de Moraes, D Heidrich… - … Acta Part A: Molecular …, 2024 - Elsevier
Fungal melanin contributes to the survival and virulence of pathogenic fungi, such as
Fonsecaea pedrosoi, which is responsible for causing chromoblastomycosis. The objective …

Transcription Factors Pmr1 and Pmr2 Cooperatively Regulate Melanin Biosynthesis, Conidia Development and Secondary Metabolism in Pestalotiopsis microspora

M Zhou, Z Li, Y Liu, P Zhang, X Hao, X Zhu - Journal of Fungi, 2021 - mdpi.com
Melanins are the common fungal pigment, which contribute to stress resistance and
pathogenesis. However, few studies have explored the regulation mechanism of its …

Antifungal susceptibility of the endophytic fungus Rhinocladiella similis (URM 7800) isolated from the Caatinga dry forest in Brazil

APSL de Pádua, A Koehler, DM Pagani… - Brazilian Journal of …, 2022 - Springer
The present study reports a new occurrence of Rhinocladiella similis isolated as an
endophytic fungus in the Caatinga dry tropical forest in Brazil and describes its antifungal …