[HTML][HTML] CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer

B Wang, M Wang, D Ao, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Chemokine CXC motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays
an important role in the immune system. The interaction between CXCL13 and its receptor …

The role of CXCL family members in different diseases

C Zhou, Y Gao, P Ding, T Wu, G Ji - Cell Death Discovery, 2023 - nature.com
Chemokines are a large family mediating a lot of biological behaviors including chemotaxis,
tumor growth, angiogenesis and so on. As one member of this family, CXC subfamily …

Role of chemokine systems in cancer and inflammatory diseases

H Li, M Wu, X Zhao - MedComm, 2022 - Wiley Online Library
Chemokines are a large family of small secreted proteins that have fundamental roles in
organ development, normal physiology, and immune responses upon binding to their …

Chemokines in the tumor microenvironment: implications for lung cancer and immunotherapy

H Jung, S Paust - Frontiers in Immunology, 2024 - frontiersin.org
The tumor microenvironment (TME) is a complex interconnected network of immune cells,
fibroblasts, blood vessels, and extracellular matrix surrounding the tumor. Because of its …

CXC chemokines in the pathogenesis of pulmonary disease and pharmacological relevance

K Komolafe, M Pacurari - International journal of inflammation, 2022 - Wiley Online Library
Chemokines and their receptors play important roles in the pathophysiology of many
diseases by regulating the cellular migration of major inflammatory and immune players …

Research progress on therapeutic targeting of cancer-associated fibroblasts to tackle treatment-resistant NSCLC

C Li, Y Qiu, Y Zhang - Pharmaceuticals, 2022 - mdpi.com
Non-small cell lung cancer (NSCLC) accounts for most lung cancer cases and is the leading
cause of cancer-related deaths worldwide. Treatment options for lung cancer are no longer …

[HTML][HTML] CXCR5 and TLR4 signals synergistically enhance non‐small cell lung cancer progression

JH Shin, MJ Kim, JY Kim, Y Kang, DH Kim… - Clinical and …, 2024 - ncbi.nlm.nih.gov
Dear Editor, Chemokines and their receptors play essential roles in neoplastic
transformation, tumour cell growth and survival, and organ-specific metastasis during …

MXRA8 is an immune-relative prognostic biomarker associated with metastasis and CD8+ T cell infiltration in colorectal cancer

L Tan, D Fu, F Liu, J Liu, Y Zhang, X Li, J Gao… - Frontiers in …, 2023 - frontiersin.org
Background Colorectal cancer (CRC) is the second most common cause of cancer-related
deaths worldwide. Tumor metastasis and CD8+ T cell infiltration play a crucial role in CRC …

High Expression of THBS1 Leads to a Poor Prognosis in Papillary Thyroid Cancer and Suppresses the Anti-Tumor Immune Microenvironment

A Jin, J Zhou, P Yu, S Zhou… - Technology in Cancer …, 2022 - journals.sagepub.com
Objectives: To study the role of thrombospondin-1 (THBS1) in papillary thyroid cancer (PTC)
prognosis and the immune microenvironment. Methods: A retrospective cohort study was …

The role of CXC chemokines in cancer progression

T Wu, W Yang, A Sun, Z Wei, Q Lin - Cancers, 2022 - mdpi.com
Simple Summary CXC chemokines are small molecules and secretory peptides, which are
significantly associated with cancer progression. Aberrant expression of CXC chemokines is …