Therapeutic drug monitoring of everolimus: a consensus report

M Shipkova, DA Hesselink, DW Holt… - Therapeutic drug …, 2016 - journals.lww.com
In 2014, the Immunosuppressive Drugs Scientific Committee of the International Association
of Therapeutic Drug Monitoring and Clinical Toxicology called a meeting of international …

Recent advances in mammalian target of rapamycin inhibitor use in heart and lung transplantation

NM Fine, SS Kushwaha - Transplantation, 2016 - journals.lww.com
The mammalian target of rapamycin (mTOR) inhibitors sirolimus and everolimus are
increasingly used in cardiothoracic transplantation. Several recent clinical trials have …

Management of side effects of mTOR inhibitors in tuberous sclerosis patients

K Sadowski, K Kotulska, S Jóźwiak - Pharmacological Reports, 2016 - Springer
Abstract mTOR inhibitors represent a relatively new therapeutic option in the management of
patients affected by tuberous sclerosis complex (TSC). Randomized clinical trials support …

Corticosteroid-free kidney transplantation improves growth: 2-year follow-up of the TWIST randomized controlled trial

NJA Webb, SE Douglas, A Rajai, SA Roberts… - …, 2015 - journals.lww.com
Background Corticosteroid withdrawal (CW) after pediatric kidney transplantation potentially
improves growth while avoiding metabolic and other adverse events. We have recently …

The role of everolimus in liver transplantation

R Ganschow, JM Pollok, M Jankofsky… - Clinical and …, 2014 - Taylor & Francis
During the last 5 decades, liver transplantation has witnessed rapid development in terms of
both technical and pharmacologic advances. Since their discovery, calcineurin inhibitors …

mTOR inhibitors in pediatric kidney transplantation

L Pape, T Ahlenstiel - Pediatric nephrology, 2014 - Springer
The mammalian target of the rapamycin (mTOR) inhibitors sirolimus and everolimus are
increasingly being used in pediatric kidney transplantation in different combinations and …

Growing experience with m TOR inhibitors in pediatric solid organ transplantation

R Ganschow, L Pape, E Sturm, J Bauer… - Pediatric …, 2013 - Wiley Online Library
Controlled trials of m TOR inhibitors in children following solid organ transplantation are
scarce, although evidence from prospective single‐arm studies is growing. Everolimus with …

Normal adult height after steroid‐withdrawal within 6 months of pediatric kidney transplantation: a 20 years single center experience

B Klare, CR Montoya, DC Fischer… - Transplant …, 2012 - Wiley Online Library
Long‐term corticosteroid treatment impairs growth in children after kidney transplantation
(KTx). The impact of steroid withdrawal with respect to adult height remains to be elucidated …

Malignancies after pediatric kidney transplantation: more than PTLD?

M Mynarek, K Hussein, HH Kreipe… - Pediatric Nephrology, 2014 - Springer
Post-transplant lymphoproliferative disease (PTLD) is the most frequent malignant
complication of transplantation in childhood. Even with modern post-transplant …

Everolimus and reduced calcineurin inhibitor therapy in pediatric liver transplant recipients: Results from a multicenter, prospective study

R Ganschow, BG Ericzon, A Dhawan… - Pediatric …, 2017 - Wiley Online Library
Abstract In a 24‐month, multicenter, single‐arm, prospective study, 56 pediatric liver
transplant patients with or without basiliximab induction were converted at 1‐6 months post …